Short CV/Education and training

Current Position

  • Since 2015
    Director of the CNRS Unit UMR 3691 “Cell dynamics in physiology and pathology”

  • Since 2011
    Principal Investigator of the Cell Polarity, Migration and Cancer Unit, Institut Pasteur/UMR 3691 CNRS, Paris, France

  • Since 2010
    Senior staff scientist (‘Directrice de Recherche’) CNRS

  • Since 2006
    Professor at the Ecole Polytechnique, Palaiseau, France

Previous Positions

  • 2006 – 2011
    Principal Investigator of the 5 year group “Cell Polarity and Migration”, Institut Pasteur/UMR 3691 CNRS, Paris, France

  • 2003 – 2005
    Independent Researcher in Pr. Daniel Louvard’s Laboratory, Institut Curie – UMR144 CNRS, Paris, France, Role of tumor suppressor genes in astrocyte polarity

  • 1999 – 2003
    Post-doctoral training in Pr. A. Hall’s Laboratory, MRC-LMCB, University College London, Londres, UK, Role of Rho GTPases in astrocyte polarization and migration.

  • 1995 – 1999
    PhD student in Pr. A. D. Strosberg’s Laboratory. Supervisor: Pierre-Olivier Couraud, Institut Cochin de Génétique moléculaire- UMR CNRS, Paris, France, Molecular mechanisms controling leukocyte infiltration through the blood- brain barrier


  • 2006
    Authority to Supervise Research (‘Habilitation à Diriger des Recherches’).Université Paris 6

  • 1998
    Ph.D., Immunology, Insitut Pasteur-Université Paris 6

  • 1995
    Agrégation en Sciences de la Vie et de la Terre. Highest degree for teachers

  • 1991 – 1995
    Student at the Ecole Normale Supérieure, Paris

Selected publications

  • De Pascalis C, Pérez-González C, Seetharaman S, Boëda B, Vianay B, Burute M, Leduc C, Borghi N, Trepat X, Etienne-Manneville S. Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts. The Journal of Cell Biology, 2018 Sep 3;217(9):3031-3044. doi: 10.1083/jcb.201801162. Epub 2018 Jul 6

  • Leduc C, Etienne-Manneville S. Regulation of microtubule-associated motors drives the polarization of the intermediate filament network. J. Cell Biol. 2017. Jun 5;216(6):1689-1703.

  • F. Peglion, F. Llense, S. Etienne-Manneville. 2014. Adherens junction treadmilling during collective migration. Nat. Cell Biol. Jul; 16(7):639-51.

  • Y. Sakamoto, B. Boëda, S. Etienne-Manneville. 2013. APC binds intermediate filaments and is required for their reogranization during cell migration. J. Cell Biol. Feb 4;200(3):249-58.

  • N. Osmani, F. Peglion, P. Chavrier, S. Etienne-Manneville. 2010 Arf6 controls cell polarity by regulating Cdc42 trafficking and activation. J. Cell Biol. 191(7):1261-9.

  • I. Dupin, E. Camand, N. Osmani, S. Etienne-Manneville. 2009. Classical cadherins control nucleus and centrosome position and cell polarity. J. Cell Biol. 185(5):779-86.

  • S. Etienne-Manneville, A. Hall. 2003. Cdc42 regulates GSK3b and adenomatous polyposis coli (APC) to control cell polarity. Nature 421 : 753-756.

  • S. Etienne-Manneville, A. Hall. 2001. Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCz. Cell 106 : 489-498.

Complete list of publications

Media coverage

  • Etienne-Manneville S. Having it all, a scientific career and a family. Nat Cell Biol. 2018 Sep;20(9):1001. doi: 10.1038/s41556-018-0160-x.



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