Prof. Dr. Anna Akhmanova
Biological and related sciences, Cell Biology, Molecular Biology, Biochemistry, Microscopy
Biological and related sciences
Molecular Medicine
RNA editing / ADARs / transcriptome / cancer
NUHS-Mochtar Riady Pinnacle Awards-High Achiever Award, 2018
EMBO Young Investigator Program (YIP), 2018
Yong Loo Lin School of Medicine Young Researcher Of the Year Award, 2017
President Assistant Professorship, National University of Singapore, 2015
Science and Technology Award of Higher Education of China (Second Class), Ministry of Education, China, 2014
NUS Young Investigator Award, National University of Singapore, 2014
Li Ka Shing Prize 2009/2010, Hong Kong, 2010
Young Scientist Award (Life Science Panel), Hong Kong Institution of Science, 2010
Dr KP Stephen Chang Gold Medal, The University of Hong Kong, 2010
YS and Christabel Lung Postgraduate Scholarships (The University of Hong Kong), 2009 and 2010
Hui Pun Hing Scholarship for Postgraduate Research (The University of Hong Kong), 2009
Chinese, English
Tang SJ, Shen H, An O, Hong HQ, Li J, Song Y, Han J, Tay DJ, Ng VHE, Molias FB, Leong KW, Pitcheshwar P, Yang H, Chen L. Cis- and trans-regulation of pre-mRNA splicing by RNA editing enzymes: influencing cancer development. Nature Communications, 11, Article number: 799 (2020). Impact factor: 11.88
Hong H, An Ő, Chan TH, Ng VHE, Kwok HS, Lin JS, Qi L, Han J, Tay DJ, Tang SJ, Yang H, Song YY, Molias FB, Tenen DG, Chen L. Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer. Nucleic Acids Res, 2018 May 18. Impact factor: 11.56
Qi L, Song Y, Chan TH, Yang H, Lin CH, Tay ST, Hong H, Tang SJ, Tan KT, Huang XX, Lin JS, Ng VHE, Maury JJP, Tenen DG, Chen L. An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer. Nucleic Acids Res. 2017, 45(18): 10436-10451. Impact factor: 11.56
Chan TH, Qamra A, Tan KT, Guo J, Yang H, Qi L, Lin JS, Ng VHE, Song Y, Hong H, Tay ST, Liu Y, Lee J, Rha SY, Feng Z, So JBY, The BT, Yeoh KG, Rozen S, Tenen DG, Tan P, Chen L. ADAR-mediated RNA editing predicts progression and prognosis of Gastric Cancer. Gastroenterology. 2016,151(4):637-650. Impact factor: 20.77
Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L*. A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma. Gut. 2014, 63(5):832-43. Impact factor: 17.02
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Biological and related sciences, Cell Biology, Molecular Biology, Biochemistry, Microscopy
Biological and related sciences, Evolutionary biology, Evolutionary genetics
Biological and related sciences, Molecular biology, molecular microbiology, biochemistry, membrane protein biochemistry
Biological and related sciences, Health, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology