Short CV/Education and training

  • 2000 – 2003
    The Technion – Israel Institute of Technology, B.A. in Molecular Biochemistry, Graduated with honors (cum laude)

  • 2004 – 2006
    The Technion – Israel Institute of Technology, M.Sc. in Biochemistry [Without thesis, moved on to the direct PhD program]

  • 2006 – 2010
    The Technion – Israel Institute of Technology, Ph.D in Biochemistry

  • 2010 – 2016
    University of Toronto, Department of Molecular Genetics, Biochemistry and Chemistry, Toronto, ON, Canada. Post-doctoral Fellowship. Host: Prof. Lewis Kay. Topics: Structural and functional study of Hsp104/ClpB and Hsp70/DnaK bi-chaperone system by novel solution NMR techniques.

Selected publications

  • Sekhar A*, Rosenzweig R*, Bouvignies G, Kay LE. Hsp70 biases the folding pathways of client proteins. Proc Natl Acad Sci U S A. 2016 May 17;113(20):E2794-801. doi: 10.1073/pnas.1601846113. * Both authors contributed equally to this work.

  • Rosenzweig R, Kay LE. (2015). Solution NMR Spectroscopy Provides an Avenue for the Study of Functionally Dynamic Molecular Machines: The Example of Protein Disaggregation. J Am Chem Soc. 2016 Feb 10;138(5):1466-77

  • Rosenzweig R, Farber P, Velyvis A, Rennella E, Latham MP, Kay LE. ClpB N-terminal domain plays a regulatory role in protein disaggregation. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50): pp 6872-81.

  • Sekhar A*, Rosenzweig R*, Bouvignies G, Kay LE. Mapping the conformation of a client protein through the Hsp70 functional cycle. Proc Natl Acad Sci U S A. 2015, Aug 18; 112 (33), pp 10395-400. * Both authors contributed equally to this work.

  • Rosenzweig R, Kay LE. (2014). Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR. Annu Rev Biochem. 2014; 83, 291-315.

  • Rosenzweig R, Moradi S, Zarrine-Afsar A, Glover JR, Kay LE. Unraveling the mechanism of protein disaggregation through a ClpB-DnaK interaction. Science. 2013 Mar 1;339(6123) pp 1080-1083.


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