Dr. Sheena Cruickshank

• PhD in Mucosal Immunology, University of Leeds

• BSc Biochemistry & Immunology, Strathclyde University

• Bramhall M, Flórez-Vargas O, Stevens R, Brass A, Cruickshank S. Quality of methods reporting in animal models of colitis. Inflammatory Bowel Diseases 2015, 21; 1248–1259

• Denes A, Coutts G, Lénárt N, Cruickshank SM, Pelegrin P, Skinner J, Rothwell N, Allan SM, Brough D. AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3 Proceedings of the National Academy of Sciences of the USA 2015 112 (13): 4050–4055

• Bowcutt R, Bramhall M, Logunova L. Wilson J, Booth C, Carding SR, Grencis RK, Cruickshank SM. A role for the pattern recognition receptor Nod2 in mediating recruitment of CD103+ dendritic cells to the colon in response to infection. Mucosal Immunol 2014 7(5):1094-105.

• Campbell L, Williams H, Crompton R, Cruickshank SM, M Hardman. Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound healing response. J Pathol 2013 229: 121–131.

• Dalton JE, Cruickshank SM, Egan CE, Mears L, Newton DJ, Lawrence B, English N, White S, Howell G, Else KJ, Gubbels M, Striepen B, Smith J and SR. Carding. A subset of TCRgd+ intraepithelial lymphocytes are required to maintain epithelial tight junction integrity and intestinal barrier function. 2006 Gastroenterology

• Ashcroft AJ, Cruickshank S, Croucher PI, Perry MJ, Rollinson SJ, Lippitt JM, Child JA, Dunstan C, Morgan GJ, Carding SR. Colonic Dendritic Cells, colitis and T cell-mediated bone destruction are modulated by recombinant Osteoprotegerin. Immunity. 2003 19: 849-861

• Developing biomarkers for predicting IBD flare and relapse

• Elucidating function of eosinophils in gut associated tissue

• Defining epithelial barrier properties and how they confer resistance or susceptibility to infection/inflammation

• Trustee in British Society of Immunology

• Member BSG, BSI

• Appeared on BBC Breakfast, BBC1 news, Sky news and talked on radio 4, 5 and various other local and national radio channels

Other activities and achievements/family

• I do a lot of public engagement work and combine my research with my outreach work.

• I am married with two children.

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