Prof. Lital Alfonta
Biological and related sciences, Physical sciences, Bioelectrochemistry, Synthetic Biology, Chemical Biology
Biological and related sciences
Immunology, Parasitology, Genetics, Molecular and Cellular Biology
Malaria, Mosquito, Anopheles gambiae, Host-pathogen interactions, Insect immunity, Genetics, Bioinformatics
Sanofi – Institut Pasteur award for young biomedical scientists, 2012
Lecture at the Palais de l'Elysée for the 3rd international biomedical research meeting organized by the French president, 2011
ERC Starting grant, 2010
EMBO long term fellowship, 2006
English, French, German
Blandin SA, Wang-Sattler R, Lamacchia M, Gagneur J, Lycett G, Ning Y, Levashina EA, Steinmetz LM (2009). Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae. Science 326, 147-150.
Fraiture M, Baxter RH, Steinert S, Chelliah Y, Frolet C, Quispe-Tintaya W, Hoffmann JA, Blandin SA, Levashina EA (2009). Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium. Cell Host Microbe 5, 273-284.
Blandin SA, Marois E, Levashina EA (2008). Antimalarial responses in Anopheles gambiae: from a complement-like protein to a complement-like pathway. Cell Host Microbe 3, 364-374.
Blandin S, Shiao SH, Moita LF, Janse CJ, Waters AP, Kafatos FC, Levashina EA (2004). Complement-like protein TEP1 is a determinant of vectorial capacity in the malaria vector Anopheles gambiae. Cell 116, 661-670.
Blandin S, Moita LF, Kocher T, Wilm M, Kafatos FC, Levashina EA (2002). Reverse genetics in the mosquito Anopheles gambiae: targeted disruption of the Defensin gene. EMBO Rep 3, 852-856.
Genetic analysis of mosquito resistance to malaria parasites.
Subversive redox substrates to block malaria parasite development in mosquito vectors.
Reviewer for scientific journals: PLoS, Science, Cellular Microbiology Trends in Parasitology, BMC, Immunology and Cell Biology, Acta Tropica, J. Insect Physio., Brain Research, Wiley-VCH
Reviewer for grant agencies: ANR (France, as a referee and as a member of a selection committee), Wellcome Trust (UK), Foundation for Science and Technology (Portugal)
Two of my publications (as first author) received a large coverage from the media: I gave two interviews for the German television, and several interviews for local and international radio stations (BBC program "Science in Action", Columbian National Public Radio, German SWR2 Campus Radio). These studies were also covered by many international scientific journals, magazines, newspapers and websites including: This week in Science, Bioworld International, Science Daily, Sueddeutsche Zeitung (Germany), Aerzte Zeitung (Germany), Der Bund (Switzerland), Sciences et Avenir (France), Publico (Portugal and Spain), Correio Braziliense (Brazil), El Dictamen (Mexico), Daily India (India)...
Direction of Inserm unit U963, IBMC, Strasbourg, France: "Immune response of the malaria vector Anopheles gambiae", since 2013
Research scientist at Inserm, since 2007
Family: 3 children
Other activities: I enjoy reading, sports (triathlon, hiking) and cooking. I participated in scientific vulgarisation programs (European Learning Lab for Life Sciences)
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Biological and related sciences, Physical sciences, Bioelectrochemistry, Synthetic Biology, Chemical Biology
Biological and related sciences, Evolution, genomics, bioinformatics
Biological and related sciences, Environment, Plant Ecology, Conservation Biology, Landscape Genomics
Biological and related sciences, Evolutionary biology, Evolutionary genetics