Short CV/Education and training

  • 1994
    Ph.D, Hungarian Academy of Sciences

  • 1985 – 1991
    Research Assistant, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary

  • 1991
    Affiliation with Biological Research Center of Hungarian Academy of Sciences, Szeged, Hungary

  • 1991 – 1995
    Postdoctoral Associate, U. of Minnesota, USA

  • 1995 – 1997
    Research Associate, U. of Minnesota, USA

  • 1997 – 1999
    EMBO fellow, The Netherlands Cancer Institute, NL

  • 1999 – 2004
    Postdoctoral Scientist, Max Delbrück Center for Molecular Medicine, Berlin, Germany

  • 2004 – 2011
    Group leader – junior, Max Delbrück Center for Molecular Medicine, Berlin, Germany

  • 2009 – 2011
    Guest Professor at the Medical University Debrecen, Hungary

  • since 2011
    Group leader – permanent, Max Delbrück Center for Molecular Medicine, Berlin, Germany

Selected publications

Selected Publications (out of 76) h-index 27, citation 3217

  • Ivics Z, Izsvák Z, Medrano G. Chapman KM, Hamra FK Sleeping Beauty Transposon Mutagenesis in Rat Spermatogonial Stem Cells. 2011; Nature Prot 8;6(10):1521-35

  • Belay E, …, Izsvák Z, Vandendriessche T, Chuah MK, Novel Hyperactive Transposons for Genetic Modification of Induced Puripotent and Adult Stem Cells: A Non-Viral Paradigm for Coaxed Differentiation. 2010; Stem Cells (10):1760-71.

  • Izsvák Z, et al., Generating Knockout Rats by Sleeping Beauty Transposon Mutagenesis in Spermatogonial Stem Cells. 2010; Nature Methods 7(6):443-5.

  • Wang Y, …, Izsvák Z, A Novel Active Endogenous Retrovirus Family Contributes to Genome Variability in Rat Inbred Strains. Genome Research 2010; 20(1):19-27.

  • Mátés L, …, Izsvák Z, Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates. Nature Genet. 2009; 41(6):753-61.

  • Ivics Z., …, Izsvák Z, Transposon-mediated genome manipulations in vertebrates. Nature Methods 2009; 6(6):415-22.

  • Sinzelle L., …, Izsvák Z, and Ivics Z, Transposition of a Reconstructed Harbinger Element in Human Cells and Functional Homology with Two Human Cellular Genes Proc. Natl. Acad. Sci. USA, 2008; 105(12):4715-2

  • Ivics Z, ..., Izsvák Z, Targeted Sleeping Beauty Transposition in Human Cells. 2007; Mol. Therapy 15(6):1137-44

  • zsvák Z, et al., (2004) Healing the wounds inflicted by Sleeping Beauty transposition by double-strand break repair in mammalian somatic cells. Mol. Cell 13:279-290.

  • Yant SR, … Izsvák Z, Kay MA, Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. 2000; Nature Genet. 25:35-41

Membership in scientific bodies/juries

  • Advisor of the Danish Council for Strategic Research

  • American Society of Gene and Cell Therapy

  • European Science Foundation – reviewer

  • European Society of Gene and Cell Therapy

  • First Secretary of the EURYIAS Academy (Candidate)

  • Guest editor of a special issue in Seminars in Cancer Biology, “Repetitive elements and genome instability” – containing 8 articles

  • Guest editor of a special issue of semi entitled “Transposons in vertebrate functional genomics” containing 16 review articles written by leaders of the field, and accessible at

  • Inventor of 9 granted and pending patents in transposon technology


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