Short CV/Education and training

  • 2013
    Habilitation (Habilitation à diriger des recherches), Université Paris Descartes

  • 2012
    Chargé de recherche INSERM and Principal Investigator (Institut Curie)

  • 2006
    PhD in Immunology, Université Paris Diderot

  • 2002
    Master's degree in Immunology, Université Pierre et Marie Curie, Paris, France

  • 1999
    Pre-doctoral program, Biology department, Ecole Normale Supérieure, Paris, France

Selected publications

  • Coillard A, Guyonnet L, De Juan A, Cros A, Segura E. (2021). TLR or NOD receptor signaling skews monocyte fate decision via distinct mechanisms driven by mTOR and miR-155. PNAS 118 (43) e2109225118.

  • De Juan A and Segura E (2021). Modulation of Immune Responses by Nutritional Ligands of Aryl Hydrocarbon Receptor. Front. Immunol. 12: 1948.

  • Coillard A and Segura E (2021). Antigen presentation by mouse monocyte-derived cells: Re-evaluating the concept of monocyte-derived dendritic cells. Molecular Immunology. 135: 165-169.

  • Villar J and Segura E (2020). Decoding the Heterogeneity of Human Dendritic Cell Subsets. Trends Immunol. 41(12): 1062-1071.

  • Durand M, Walter T, Pirnay T, Naessens T, Gueguen P, Goudot C, Lameiras S, Chang Q, Talaei N, Ornatsky O, Vassilevskaia T, Baulande S, Amigorena S, Segura E. (2019). Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses. J Exp Med. 216(7): 1561-81.

  • Coillard A and Segura E (2019). In vivo Differentiation of Human Monocytes. Front. Immunol. 10:1907.

  • Tang-Huau TL, Gueguen P, Goudot C, Durand M, Bohec M, Baulande S, Pasquier B, Amigorena S, Segura E (2018). Human in vivo-generated monocyte-derived dendritic cells and macrophages cross-present antigens through a vacuolar pathway. Nature Communications 9, 2570. DOI: 10.1038/s41467-018-04985-0

  • Goudot C, Coillard A, Villani AC, Gueguen P, Cros A, Sarkizova S, Tang-Huau TL, Bohec M, Baulande S, Hacohen N, Amigorena S, Segura E (2017). Aryl hydrocarbon receptor controls monocyte differentiation into dendritic cells versus macrophages. Immunity. 47(3): 582-596.

Complete list of publications

Selected projects

The aims of our current research are:

  • to better characterize the properties of human antigen presenting cells

  • to unravel the molecular regulators that drive monocyte differentiation towards DC versus macrophage

  • to decipher the role of Aryl Hydrocarbon Receptor in immune responses

Membership in scientific bodies/juries

  • Member of French Society of Immunology, European Macrophage and Dendritic cell Society, and French Dendritic Cell Society

  • Former President of CFCD (French Dendritic Cell Society), 2018 – 2020

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • Member of the Editorial Board of European Journal of Immunology

  • Associate Editor of Frontiers in Immunology, section “Antigen Presenting Cell Biology”


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