Short CV/Education and training

  • 1984 – 1986
    Bachelor/Vordiplom in Biology, Johannes-Gutenberg University Mainz, Germany

  • 1986 – 1989
    Major/Diplom in Biology, Philipps-University Marburg, Germany

  • 1990 – 1993
    Ph.D., Georg-August-University Göttingen, Germany

  • 1994 – 1996
    Postdoctoral scholarship (DFG), Harvard Medical School, Boston,USA

  • 1996 – 1997
    Postdoctoral-Associate, Harvard Medical School, Boston,USA

  • 1998 – 2001
    Helmholtz-Scholarship, MDC

  • 2001 – 2005
    Senior Scientist, MDC

  • Since 2006
    Research Group Leader, Max-Delbrück-Center for Molecular Medicine (MDC)

  • 2008
    Priv. Doz., Charité-University Medicine Berlin, Germany

Selected publications

  • Heinig K, Gätjen M, Grau, M, Stache, V, Anagnostopoulos I, Gerlach, K, Niesner R, Cseresnyes Z, Hauser A, Lenz P, Hehlgans T, Brink R, Westermann J, Dörken B, Lipp M, Lenz G, Rehm A, Höpken UE (2014). Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B cell activation and proliferation. Cancer Discovery 4:1449-1465.

  • Rehm A, Gätjen M, Gerlach K, Scholz F, Mensen A, Gloger M, Heinig K, Lamprecht B, Mathas S, Begay V, Leutz A, Lipp M, Dörken B, Höpken UE (2014). Dendritic cell-mediated survival signals in Eμ-Myc B cell lymphoma depend on the transcription factor C/EBPβ. Nature Communication 5:5057-5070.

  • Wichner K, Fischer A, Winter S, Tetzlaff S, Heimesaat MM, Bereswill S, Rehm A, Lipp M, Höpken UE (2013): Transition from an autoimmune-prone state to fatal autoimmune disease in CCR7 and RORγt double-deficient mice is dependent on gut microbiota. Journal of Autoimmunity 47:58-72.

  • Herda S, Raczkowski F, Mittrücker HW, Willimsky G, Gerlach K, Kühl AA, Breiderhoff T, Willnow TE, Dörken B, Höpken UE and Rehm A. 2012. The sorting receptor Sortilin exhibits a dual function in exocytic trafficking of interferon-γ and granzyme A in T cells. Immunity 37:854-866.

  • Rehm A, Mensen A, Schradi K, Gerlach K, Wittstock S, Winter S, Büchner G, Dörken B, Lipp M and Höpken UE. 2011. Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs. Blood 118:1020-1033

Selected projects

  • Cellular and molecular dissection of the tumor-stroma interaction in B cell lymphoma/leukemia

  • Targeting the secretory pathway in CTLs to modulate their cytolytic capacity in cancer immunotherapy

  • Lymphocytic homeostasis and mucosal immunity

  • Mouse models of chronic gastrointestinal inflammation and inflammation-mediated carcinogenesis

Membership in scientific bodies/juries

  • Member of the Deutsche Krebsgesellschaft (German cancer society)

  • Spokesperson for the AEK-I working group within the Deutsche Krebsgesellschaft

  • Member of the scientific advisory committee to the Max Delbrück Centre (MDC)

  • Member of the MDC continuing education committee

  • Member of the committee "Microscopy Core Facility" (MCF)

  • Member of the MDC animal welfare committee (TSA)

  • Member of BIH Young Science at the Berlin Institute of Health (BIH)

  • MDC mentoring programme for female scientists

Additional qualifications

  • DFG-Auslandsstipendiatin

  • Helmholtzstipendiatin


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