Short CV/Education and training

  • Since 2015
    Associate Professor

  • 2011
    received a Senior research position from the Swedish research Council

  • 2007
    Young investigator award from the Swedish Cancer society. Since then PI and group leader at Karolinska Institutet

  • 2002 – 2007
    Post Doc in Camilla Sjögrens and Prof Katsuhiku Shirahiges labs at Karolinska institutet and Tokyo Institute of Technology Japan.

  • 2002
    PhD in Cell and molecular biology/Immunology

Selected publications

  • BOT C, PFEIFFER A, GIORDANO F, MANJEERA EDARA D, DANTUMA N, AND STRÖM L. Two independent mechanisms for recruitment of the mammalian cohesin loader NIPBL to DNA damage. J Cell Science (2017), 130: 1134, PMID: 28167679

  • LINDGREN E, GIORDANO F, HÄGG S, BJÖRKEGREN J, AND STRÖM L. Inactivation of the cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break Cell cycle (2014) 13: 3645 PMID: 25483075

  • DAHLBERG, CIM, HE M, VISNES T, TORRES ML, CORTIZAS EM, VERDUN RE, WESTERBERG LS, SEVERINSON E, AND STRÖM L. A Novel Mouse Model for the Hyper-IgM syndrome: A Spontaneous activation-induced cytidine deaminase mutation leading to Complete Loss of Ig Class Switching and reduced somatic hypermutation J Immunol, (2014), 193:4732, PMID: 25252954

  • VISNES T, GIORDANO F, KUZNETSOVA A, SUJA J, LANDER AD, CALOF AL, STRÖM L. Localisation of the SMC loading complex Nipbl/Mau2 during mammalian meiotic prophase I Chromosoma (2014) 123:239, PMID: 24287868

  • ENERVALD E, DU L, VISNES T, BJORKMAN A, LINDGREN E, WINCENT J, BORCK G, COLLEAUX L, CORMIER-DAIRE V, VAN GENT DC, PIE J, PUISAC B, DE MIRANDA NF, KRACKER S, HAMMARSTROM L, DE VILLARTAY JP, DURANDY A, SCHOUMANS J, STRÖM L†, PAN-HAMMARSTRÖM Q†. A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination J Exp Med (2013) 210; 2503, PMID: 24145515, †shared corresponding authors

  • ENERVALD E, LINDGREN E, KATOU Y, SHIRAHIGE K, STRÖM L. Importance of Polη for damage-induced cohesion reveals differential regulation of cohesion establishment at the break site and genome-wide PLoS Genetics (2013) 9;1 e1003158, PMID: 23326240

  • DORSETT D, STRÖM L. The Ancient and Evolving Roles of Cohesin in Gene Expression and DNA Repair Curr Biol (2012) 22; R240, PMID: 22497943

  • STRÖM L, KARLSSON C, LINDROOS HB, WEDAHL S, KATOU Y, SHIRAHIGE K, SJÖGREN C. Postreplicative formation of cohesion is required for repair and induced by a single DNA break Science (2007) 317; 242, PMID: 17626884

  • STRÖM L, LINDROOS HB, SHIRAHIGE K, SJÖGREN C. Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair Mol Cell (2004) 16; 1003, PMID: 15610742


Membership in scientific bodies/juries

  • Evaluation for an IndianAlliance Fellowship from the Wellcome Trust/DBT India Alliance, 2015

  • Evaluation of Nomination to The Wittgenstein award, Univeristy of Vienna, Switzerland, 2012

  • Reviewer of Professorship nomination for wellcometrust, at University of Dundee, 2011

  • Evaluation of application to the Czech Science Foundation, 2017

  • Evaluation of applications for PhD student financing grants, Karolinska Institutet, 2016

  • Chair of the committee for Novartis Post Doc positons, 2016

  • Evaluation of application submitted to the India-Isreal joint research program, 2015

  • Evaluation of Research applications to Israel Science Foundation , 2013, 2014

  • Reviewer of “Thalis” The Greek Ministry of Education´s call for proposals for; Enhancement of Interdisciplinary or/and Interdepartmental Research and Innovation in the Greek Universities and Research Institutions, Stage 1 and 2, 2011

  • Faculty opponent, Trondheim University, since 2013

  • Member of 13 PhD thesis committees, since 2011

  • Evaluations of three nominations for, since 2011

  • Member of 14 admission or mid-point review committees, since 2010

Soft Skills/Other activities and achievements

Additional interests

  • 2015 Guest Editor PLoS Genetics

  • Since 2015 Member of the basic science editorial board for Oncotarget


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News

  1. "Knowledge will always have a purpose"

    Lena Ström studies DNA repair mechanisms in yeast and mammalian cells. Her work can be described as “basic" science – research that primarily serves as knowledge generator, and that does not yet have direct medical or technological applications. AcademiaNet spoke with Dr Ström about basic science and her field of research.