Short CV/Education and training

  • 2000 – 2003
    BSc in Molecular Biology and Genetics – RHUL, London, UK

  • 2003 – 2004
    Master1 in Cell Biology and Physiology – University of Paris XI, France

  • 2004 – 2005
    Master2 in Cell Biology – University of Paris V, France

  • 2005 – 2008
    PhD in Cell Biology – Cochin Institute, University Paris V, France

  • 2009 – 2012
    Postdoc – Molecular Virology Lab, IGH (UPR 1142), Montpellier, France

  • 2012 – 2014
    CR2 CNRS – Molecular Virology Lab., IGH (UPR 1142), Montpellier, France

  • 2014
    HDR – University of Montpellier I, France

  • 2015
    Group Leader – Molecular basis of Cancer-Related Inflammation Lab., IGH (UPR 1142), Montpellier, France

Selected publications

  • Book Chapter: Brégnard C, Guerra J, Laguette N. The SLX4 complex and HIV replication. Book Chapter. The Encyclopedia of AIDS. In press.

  • Laguette N*, Benkirane M*. Shaping of the host cell by viral accessory proteins. Front Microbiol. 2015 Feb 23;6:142. Invited Review. * Corresponding authors

  • Invited Review: Brégnard C, Benkirane M*, Laguette N*. 2014 DNA damage repair machinery and HIV escape from innate immune sensing. Front Microbiol. 5:176. Review. * Corresponding authors

  • Laguette N*, Brégnard C, Hue P, Basbous J, Yatim A, Larroque M, Kirchhoff F, Constantinou A, Sobhian B and Benkirane* M. 2014. Premature Activation of the SLX4 Complex by Vpr Promotes G2/M Arrest and Escape from Innate Immune Sensing Cell 156(1-2):134-45 * Corresponding authors

  • Cribier A, Descours B, Valadao AL, Laguette N, Benkirane M. 2013. Phosphorylation of SAMHD1 by Cyclin A2/CDK1 Regulates Its Restriction Activity toward HIV-1. Cell Rep 3: 1036-43.

  • Descours B, Cribier A, Chable-Bessia C, Ayinde D, Rice G, Crow Y, Yatim A, Schwartz O, Laguette N, Benkirane M. 2012. SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells. Retrovirology 9: 87.

  • Brandariz-Nuñez A, Valle-Casuso J, White T E, Laguette, N, Benkirane M, Brojatsch J, Diaz-Griffero F. 2012. Role of SAMHD1 Nuclear Localization in Lentiviral Restriction. Retrovirology. 9(1):49.

  • Lahouassa H, Daddacha W, Hofmann H, Ayinde D, Logue EC, Dragin L, Bloch N, Maudet C, Bertrand M, Gramberg T, Pancino G, Priet S, Canard B, Laguette N, Benkirane M, Transy C, Landau NR, Kim B, Margottin-Goguet F. 2012. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat Immunol 13: 223-8

  • Laguette N*, Rahm N*, Sobhian B, Chable-Bessia C, Munch J, Snoeck J, Sauter D, Switzer WM, Heneine W, Kirchhoff F, Delsuc F, Telenti A, Benkirane M. 2012. Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein. Cell Host Microbe * First authors

  • Invited Review: Laguette N*, Benkirane M*. 2011. How Samhd1 changes our view of viral restriction. Trends Immunol * Corresponding authors

Complete list of publications


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