Dr. Jessica Abbott
Biological and related sciences, Evolutionary biology, Evolutionary genetics
Biological and related sciences
molecular and cell biology
mitochondria, cellular protein homeostasis
Laureate of the Welcome Programme from the Foundation for Polish Science
EMBO Installation Grantee
English, Polish
Chacinska, A., Lind, M., Frazier, A.E., Dudek, J., Meisinger, C., Geissler, A., Sickmann, A., Meyer, H.E., Truscott, K.N., Guiard, B., Pfanner, N., Rehling, P. (2005). Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120, 817-29.
Chacinska, A., Pfannschmidt, S., Wiedemann, N., Kozjak, V., Sanjuán Szklarz, L.K., Schulze-Specking, A., Truscott, K.N., Guiard, B., Meisinger, C., Pfanner, N. (2004). Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J. 23, 3735-46.
Sickmann, A., Reinders, J., Wagner, Y., Joppich, C., Zahedi, R., Meyer, H.E., Schönfisch, B., Perschil, I., Chacinska, A., Guiard, B., Rehling, P., Pfanner, N., Meisinger, C. (2003). The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A. 100, 13207-12.
Chacinska, A., Koehler, C.M., Milenkovic, D., Lithgow, T., Pfanner, N. (2009). Importing mitochondrial proteins: machineries and mechanisms. Cell 138, 628-644.
von der Malsburg, K., Müller, J.M., Bohnert, M., Oeljeklaus, S., Kwiatkowska, P., Becker, T., Loniewska-Lwowska, A., Wiese, S., Rao, S., Milenkovic, D., Hutu, D.P., Zerbes, R.M., Schulze-Specking, A., Meyer, H.E., Martinou, J.C., Rospert, S., Rehling, P., Meisinger, C., Veenhuis, M., Warscheid, B., van der Klei, I.J., Pfanner ,N.*, Chacinska, A.*, van der Laan, M. (2011). Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis. Developmental Cell, 21, 694-707.
(*co-corresponding author)
Bragoszewski, P., Gornicka, A., Sztolsztener, M.E., and Chacinska, A. (2013). The ubiquitin-proteasome system regulates mitochondrial intermembrane space proteins. Mol Cell Biol 33, 2136-48.
Wrobel, L., Trojanowska, A., Sztolsztener, M.E., and Chacinska, A. (2013). Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria. Mol Biol Cell 24, 543-554.
Sztolsztener, M.E., Brewinska, A., Guiard, B., and Chacinska, A. (2013). Disulfide bond formation: sulfhydryl oxidase ALR controls mitochondrial biogenesis of human MIA40. Traffic 14, 309-320.
Gornicka, A., Bragoszewski, P., Chroscicki, P., Wenz, L.S., Schulz, C., Rehling, P., Chacinska, A. (2014). A discrete pathway for the transfer of intermembrane space proteins across the outer membrane of mitochondria . Mol. Biol. Cell 25, 3999-4009.
Sokol, A.M., Sztolsztener, M.E., Wasolewski, M., Heinz, E., Chacinska, A. (2014). Mitochondrial protein translocases for survival and wellbeing. FEBS Lett. 588, 2484-2485.
Referee for a number of international scientific journals including the EMBO Journal, EMBO Reports, Nature Structural and Molecular Biology, Cell Reports, PNAS, Journal of Cell Biology, Journal of Molecular Biology, Eukaryotic Cell, BBA, Molecular Biology of the Cell.
Referee and/or panel expert for funding institutions: Human Frontier Science Program, Strasbourg; Australian Research Council; BBSRC, UK; DFG, Germany; Estonian Science Foundation, Estonia; Foundation for Polish Science; German-Israeli Foundation for Scientific Research and Development (GIF); National Science Centre, Poland.
Panel expert of European Research Council, Foundation for Polish Sciences, National Science Centre Poland.
Member of the Scientific Board of Institute of Biochemistry and Biophysics Polish Academy of Science.
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Biological and related sciences, Evolutionary biology, Evolutionary genetics
Biological and related sciences, Evolution, genomics, bioinformatics
Biological and related sciences, Health, Cell Biology, Cellular signaling, Cancer biology, Cancer therapy
Biological and related sciences, Evolutionary biology, Animal behaviour, Gender studies, Science studies
Prof. Agnieszka Chacińska of the International Institute of Molecular and Cell Biology in Warsaw received the 6th COPERNICUS Polish-German Scientific Award, together with Prof. Peter Rehling of the Göttingen University Medical Centre.