Short CV/Education and training

  • 1991
    Bachelor of Biology (Biochemistry), Valencia University

  • 1992
    Undergraduate research training, University Valencia, Spain

  • 1992
    Visiting research scientist, Dept. of Biochemistry, University of Leicester, UK

  • 1993
    Visiting research scientist, Dept. of Biochemistry, University of Leicester

  • 1994
    Visiting research scientist, Dept. of Biochemistry, University of Leicester

  • 1996
    PhD in Biology, University Valencia, Spain (Supervisor: Erwin Knecht)

  • 1996
    Postdoctoral Fellow, Developmental Biology, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, Signal Transduction (Supervisor: Angel Nebreda) and Neurobiology (Supervisor: Ruediger Klein)

  • 2001
    Group leader, Max-Planck-Institute of Neurobiology, Martinsried, Germany

  • 2007
    W2 Professor, Cluster of Excellence Macromolecular Complexes (CEF) Goethe University Frankfurt

  • 2010
    Call W3 Professor-Director, Institute of Cellular Biophysics, Research Center Jülich GmbH, Helmholtz Society and the Heinrich-Heine-Universität Düsseldorf (declined)

  • Since 2010
    Faculty Buchmann Institute of Molecular Life Sciences, Cluster of Excellence Macromolecular Complexes (CEF), Goethe University Frankfurt

  • Since 2011
    Faculty Forschungszentrum Translationale Neurowissenschaften (FTN), Johannes Gutenberg-Universität Mainz

  • Since 2011
    W3 Professor and Department Chair Molecular and Cellular Neurobiology, Institute of Cell Biology and Neurosciences, Biology Faculty, Goethe University Frankfurt

Selected publications

  • Senturk, A., Pfennig, S., Weiss, A., Burk, K. and Acker-Palmer, A. (2011) EphrinBs are essential components of the Reelin pathway to regulate neuronal migration. Nature, 472:356-60.

  • Sawamiphak, S., Seidel, S., Essmann, C.L., Wilkinson, G., Pitulescu, M.E., Acker, T. and Acker-Palmer, A. (2010) EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis Nature 465, 487-491.

  • Essmann, C.L., Martinez, E., Geiger, J., Zimmer, M., Traut, M., Stein, V., Klein, R. and Acker-Palmer, A. (2008) Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nature Neuroscience 11: 1035 – 1043.

  • Segura, I., Essmann, C. L., Weinges, S. and Acker-Palmer, A. (2007). Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nature Neuroscience 10: 301-310.

  • Palmer, A. and Klein, R. (2003) Multiple roles of ephrins in morphogenesis, neuronal networking, and brain function. Genes & Development 17: 1429-1450.

  • Palmer, A., Zimmer, M., Erdmann, K.S., Eulenburg, V., Porthin, A., Heumann, R., Deutsch, U., and Klein, R. (2002). EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Molecular Cell 9: 725-37.

  • Palmer, A.; Gavin, A.C. and Nebreda,A.R. (1998) A link between MAP Kinase and p34cdc2/cyclinB during oocyte maturation: p90rsk associates with and phosphorylates the p34cdc2 inhibitory kinase Myt1 EMBO J., 17: 5037-5047.

Membership in scientific bodies/juries

  • Speaker GRADE-Brain (Goethe Graduate Academy), since 2012

  • Vice-speaker of the Rhine-Main Neuroscience Network (rmn2), since 2011

  • Vice-Speaker (Frankfurt coordinator) Collaborative Research Centre SFB1080 Molecular and Cellular Mechanisms of Neuronal Homeostasis Mainz/Frankfurt

  • Member of the Board of Directors Cluster of Excellence Macromolecular Complexes (CEF), 2009 – 2012

  • Board member of the LOEWE Focus project: Neuronal Coordination Frankfurt (NeFF)

  • Board member of the LOEWE Focus project: Ocogenic signal transduction Frankfurt (OSF)

  • Member of the German National Academy of Sciences Leopoldina

  • Member of the Gutenberg Forschungskolleg

  • Member of the American Society for Biochemistry and Molecular Biology (ASBMB)

  • Member of the German Neuroscience Society

  • Member of the German Society for Cell Biology

  • Member of the German Society for Biochemistry and Molecular Biology

  • Member of the Interdisciplinary Centre for Neuroscience Frankfurt (ICNF)

  • Member of the Center for Membrane Proteomics Frankfurt (CMP)

  • Member of the Cluster of Excellence Macromolecular Complexes (CEF)

  • Member of the Cluster of Excellence Cardio-Pulmonary System (ECCPS)

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • married, 2 children


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  1. ERC Grant for Amparo Acker-Palmer

    The growth of neuronal and vascular networks is controlled by the same molecules. Now Amparo Acker-Palmer plans to study the communication between neurons and blood vessels in the brain. She hopes to use her findings to gain important insights into dementia progression, and into other mental illnesses.

  2. Cancer Cells Grow Despite Oxygen Lack

    Healthy cells reduce their growth when there is a lack of oxygen, or hypoxia. But hypoxia is a characteristic of malignant tumours. The team of Prof. Amparo Acker-Palmer from Goethe University Frankfurt and colleagues from the University of Giessen could show how cancer cells succeed at circumventing the genetic program of growth inhibition.

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