Short CV/Education and training

  • Since 2019
    Professor for Immune modulation (W2) at Ludwig-Maximilians University (LMU), Munich, Germany

  • Since 2016
    Tenured Principal Investigator, Helmholtz Zentrum München, Munich, Germany

  • 2012 – 2016
    Helmholtz Young Investigator group leader, Helmholtz Zentrum München, Munich, Germany

  • 2008 – 2012
    Research Fellow in Microbiology and Immunobiology at Harvard Medical School as a joint appointment, Boston, US

  • 2008 – 2012
    Postdoctoral scientist with a Leopoldina Fellowship at the Dana Farber Cancer Institute/Department of Cancer Immunology and Aids, Boston, US

  • 2007 – 2008
    Postdoctoral scientist at Johann Wolfgang Goethe University Frankfurt, Institute of Pharmacology/Immunopharmacology, Frankfurt, Germany

  • 2003 – 2007
    PhD thesis in Immunopharmacology, University of Frankfurt/Karolinska Institute Stockholm

  • 2001 – 2002
    Diploma Thesis in Physiology at Max-Planck Institute for Physiological and Clinical Research, Bad Nauheim, Germany

  • 1997 – 2002
    Study of Nutritional Sciences at Justus-Liebig-University, Giessen, Germany, Focus Biochemistry, Pathophysiology, Cell Biology

Selected publications

  • Scherm MG, Serr I, Zahm AM, Schug J, Bellusci S, Manfredini R, Salb VK, Gerlach K, Weigmann B, Ziegler AG, Kaestner KH, Daniel C. miRNA143-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes. Nature Communications 2019, 10, 5697

  • Becker M, Serr I, Salb VK, Ott VB, Mengel L, Blüher M, Weigmann B, Hauner H, Tschöp MH, Daniel C. Short-term cold exposure supports human Treg induction in vivo. Mol Metab 2019, doi: 10.1016/j.molmet.2019.08.002

  • Serr I, Scherm MG, Zahm AM, Schug J, Flynn VK, Hippich M, Kälin S, Becker M, Achenbach P, Nikolaev A, Gerlach K, Liebsch N, Loretz B, Lehr C-M, Kirchner B, Spornraft M, Haase B, Segars J, Küper C, Palmisano R, Waisman A, Willis RA, Kim W-U, Weigmann B, Kaestner KH, Ziegler AG, Daniel C. A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes. Sci Transl Med 2018

  • Kalin S, Becker M, Ott VB, Serr I, Hosp F, Mollah MMH, Keipert S, Lamp D, Rohner-Jeanrenaud F, Flynn VK, Scherm MG, Nascimento LFR, Gerlach K, Popp V, Dietzen S, Bopp T, Krishnamurthy P, Kaplan MH, Serrano M, Woods SC, Tripal P, Palmisano R, Jastroch M, Bluher M, Wolfrum C, Weigmann B, Ziegler AG, Mann M, Tschop MH, Daniel C. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function. Cell Metab 2017, 26, 475-492 e477

  • Serr I, Fürst RW, Ott VB, Scherm MG, Nikolaev A, Gökmen F, Kälin S, Zillmer S, Bunk M, Weigmann B, Kunschke N, Loretz B, Lehr CM, Kirchner B, Haase B, Pfaffl MW, Waisman A, Willis RA, Ziegler AG, Daniel C. miRNA92a targets KLF2 and PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. PNAS 2016, doi/10.1073/pnas.1606646113

  • Serr I, Fürst RW, Achenbach P, Scherm MG, Gökmen F, Haupt F, Sedlmeier E-M, Knopff A, Shultz L, Willis RA, Ziegler A-G, Daniel C. Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice. Nature Communications 2016, DOI: 10.1038/ncomms10991

  • von Boehmer H and Daniel C. Therapeutic opportunities for manipulating Tregs in autoimmunity and cancer. Nat Rev Drug Discovery 2013

Selected projects

  • EFSD/JDRF/Lilly Programme on Type 1 Diabetes Research Award

  • Excellence program for outstanding female scientists, Associate professorship grant, Helmholtz Association

  • CRC1054, Project Mechanisms of immune activation vs. regulation in autoimmune Type 1 Diabetes

  • JDRF Strategic Research Agreement Award

Membership in scientific bodies/juries

  • Member of the German Association of Immunologists (DGfI), 2017

  • Member of European Association for the Study of Diabetes (EASD), 2013

  • Member of the German Diabetes Association (DDG), 2012

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • One daughter born in 2019


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