Short CV/Education and training

  • 1974
    Born

  • 1994 – 1999
    Undergraduate degree in biochemistry (with distinction) from the University of Hannover, Germany

  • 1999 – 2003
    Doctoral studies at the Leibniz Institute of Neurobiology in Magdeburg, Germany

  • 2003
    Doctorate (with distinction)

  • 2003 – 2008
    Postdoctoral fellowship at the California Institute of Technology, Pasadena, USA

  • Since 2008
    Director of a German Research Foundation (DFG) Emmy Noether research group at the Leibniz Institute of Neurobiology in Magdeburg

  • Since 2012
    Director of the Institute for Pharmacology and Toxicology at the University of Magdeburg

Selected publications

  • Dieterich, D.C. et al.: In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. In: Nature Neuroscience, June 13, 2010.

  • Taylor, A.M. et al.: Microfluidic local perfusion chambers for the visualization and manipulation of synapses. In: Neuron 66, 2010. pp. 57-68.

  • Ngo, J.T. et al: Cell-selective metabolic labeling of proteins. In: Nat Chem Biol 5, 2009. pp. 715-717.

  • Kindler, S. et al: Dendritic mRNA targeting of Jacob and N-methyl-d-aspartate-induced nuclear translocation after calpain-mediated proteolysis. In: J Biol Chem 284, 2009. pp. 25431-25440.

  • Dieterich, D.C. et al.: Caldendrin-Jacob: a protein liaison that couples NMDA receptor signalling to the nucleus. In: PLoS Biol 6, 2008. e34.

  • Dieterich, D.C. et al.: Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging. In: Nat Protoc 2, 2007. pp. 532-540.

  • Dieterich, D.C. et al.: Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). In: Proc Natl Acad Sci U.S.A. 103, 2006. pp. 9482-9487.

  • Dieterich, D.C. et al.: Gliap – a novel untypical L-asparaginase localized to rat brain astrocytes. In: J Neurochem 85, 2003. pp. 1117-1125.

Review

  • Dieterich, D.C.: Chemical Reporters for the lllumination of Protein and Cell Dynamics. In: Current Opinion in Neurobiology, 2010, in press.

Book Chapter

  • Dieterich, D.C., Link, A.J.: Click Chemistry in Protein Engineering, Design, Detection and Profiling. In: Lahann, J. (ed.): Click Chemistry for Biotechnology and Materials Science, John Wiley & Sons, 2009, pp. 309-325. (ISBN 9780470699706)

Patent Applications

  • WO/2006/069203: Methods for proteomic profiling using non-natural amino acids

    WO/2007/047668: Use of non-canonical amino acids as metabolic markers for rapidly dividing cells


Selected projects

  • Developmental assembly and molecular constituents of chemical synapses

  • The neuron–glia partnership: Functions of astrocytes during neuronal development and synaptic plasticity

  • Glycoprotein dynamics at the synapse

  • Development of metabolic profiling methods based on click chemistry

Membership in scientific bodies/juries

  • Reviewer for the German Research Foundation (DFG) funding agency

  • Reviewer for scientific journals including Nature Protocols, Nature Methods, Journal of Neuroscience, Journal Proteome Research, Molecular and Cellular Proteomics, PLoS ONE

  • DFG Emmy Noether programme fellow, since 2008

  • GAIN advisory board member, 2006 – 2010

Soft Skills/Other activities and achievements

Soft Skills

  • Mentor for female PhD students and Postdocs at the California Institute of Technology (2003 – 2008) and the University of Magdeburg, Germany (since 2009)


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