Short CV/Education and training

  • 1955

  • 1956 – 1960
    Studied chemistry at Humboldt University, Berlin, and LMU Munich, Germany

  • 1962

  • 1962 – 1964
    Research associate at the Institute of Anorganic Chemistry, LMU Munich

  • 1964 – 1967
    German Research Foundation (DFG) training fellowship for 2 years, then postdoc at Johns Hopkins University, School of Medicine, Baltimore, USA

  • 1968 – 1969
    Research associate at the Max Planck Institute of Experimental Medicine, Göttingen, Germany

  • 1969 – 1985
    Department head at the German Society for Molecular Biology Research (GMBF), later renamed Society for Biotechnology Research (GBF), Braunschweig, Germany

  • 1975 – 1979
    Scientific director of the GMBF/GBF

  • 1979
    Habilitation (postdoctoral qualification) in the field of biochemistry

  • 1986 – 2002
    University professor and director of the Institute of Enzyme Technology at Heinrich Heine University, Düsseldorf, Germany

  • 1995
    Sherman Fairchild Distinguished Scholar at the California Institute of Technology, Pasadena, USA

  • Since 1995
    Member of the North Rhine-Westphalian Academy of Sciences

  • 2002

Selected publications

  • Schütte, H., Flossdorf, J. Sahm, H. and Kula, M.-R. (1976): Purification and Properties of Formaldehyde Dehydrogenase and Formate Dehydrogenase from Candida Boidinii. In: European Journal of Biochemistry. 62, 151-160.

  • Kroner, K.H., Hustedt, H. Granda, S. and Kula, M.-R. (1978): Technical Aspects of Separation Using Aqueous Two-Phase Systems in Enzyme Isolation Processes. In: Biotechnology and Bioengineering. 20, 1967-1988.

  • Wichmann, R., Wandrey, C., Bückmann, A.F. and Kula, M.-R. (1981): Continuous Enzymatic Transformation in an Enzyme Membrane Reactor with Simultaneous NADH Regeneration. In: Biotechnology and Bioengineering. 23, 2789-2802.

  • Hustedt, H., Kroner, K.H. and Kula, M.-R. (1985): Applications of Phase Partitioning in Biotechnology. In: H. Walter, D.E. Brooks and D. Fisher (Eds.): "Partitioning in Aqueous Two-Phase Systems: Theory, Methods, Uses and Applications to Biotechnology", Acadamic Press, New York, pp. 529-587.

  • Briefs, K.-G. and Kula, M.-R. (1992): Fast protein chromatography in analytical and preparative scale using modified microporous membranes. In: Chemical Engineering Science, 47, 141-149.

  • Gebauer, K., Thömmes, J. and Kula, M.-R. (1997): Breakthrough-Performance of High-Capacity Membrane Adsorbers in Protein Chromatography. In: Chemical Engineering Science, 52, 405-419.

  • Fernández-Lahore, H. M., Kleef, R., Kula, M.-R. and Thömmes, J. (1999): The influence of complex biological feedstock on the fluidization and bed stability in Expanded Bed Adsorption. In: Biotechnology and Bioengineering. 64, 484 – 496.

  • Ansorge, M. B., Kula, M.-R. (2000): Production of recombinant L-leucine dehydrogenase from Bacillus cereus in pilot scale using the runaway replication system E. coli [pIET98]. In: Applied Microbiology and Biotechnology, 53, 668-673.

  • Slusarczyk, H., Felber, St., Kula, M.-R., Pohl, M. (2000): Stabilization of NAD-dependent formate dehydrogenase from Candida boidinii by site-directed mutagenesis of cysteine residues. In: European Journal of Biocheminstry, 267, 1280-1289.

  • Frerix A, Geilenkirchen P, Müller M, Kula MR, Hubbuch J (2007): Separation of genomic DNA, RNA and open circular plasmid DNA from supercoiled plasmid DNA by combining denaturation, selective renaturation and aqueous two-phase extraction. In: Biotechnology and Bioengineering: 96 : 57 – 66.

Membership in scientific bodies/juries

  • Member of Acatech, the German National Academy of Science and Engineering, since 2004

  • Foreign associate member, US National Academy of Engineering, since 2002

  • Many years as a member of the German Chemical Society (GDCh), Dechema (Society for Chemical Engineering and Biotechnology), GBM, American Chemical Society

  • Many years of working in the pertinent committees of Dechema and the Association of German Engineers (VDI)

  • Member of the advisory board for the Technical Faculty of Lund University (LTH), Sweden

Additional qualifications

  • ca. 20 years as international coordinator between Japan and Germany in the field of enzyme technology, on behalf of the German government

  • Consultant on enzyme technology and protein purification to numerous companies in Germany and abroad

  • Reviewer for the German Research Foundation (DFG), the Alexander von Humboldt Foundation, the German Academic Exchange Service (DAAD), as well as research organisations in Europe and the USA

  • 10 years as associate editor of Biotechnology Bioengineering for the field of "Downstream Processing"; serve on the editorial boards of other pertinent professional journals

  • ca. 50 basic patents, mostly with companies


You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here


  1. Read what our members say about AcademiaNet.

Follow us

No more excuses!

  1. Please download the brochure "No more excuses" and read more about female experts in Europe, and about AcademiaNet.

Similar profiles

  1. Dr. Libertat Abad Muñoz

    Physical sciences, Physical Sciences and Technology

  2. Prof. Lital Alfonta

    Biological and related sciences , Physical sciences, Bioelectrochemistry, Synthetic Biology, Chemical Biology

  3. Prof. Dr. Núria Aliaga-Alcalde

    Physical sciences, Chemistry coordination, Chemistry, Molecular magnetism, Molecular electronics, Bioinorganics

  4. Prof. Dr. Seema Agarwal

    Physical sciences, Preparative and physical chemistry of polymersNanotechnology