Short CV/Education and training

  • 1988 – 1993
    Study of Diplom-Biopharmakologie, Ernst-Moritz-Arndt-University of Greifswald

  • 1994 – 1998
    PhD thesis, Supervisor: Prof. Michael Hecker, Institute for Microbiology, Ernst-Moritz-Arndt-University of Greifswald

  • 1999 – 2005
    Postdoctoral Researcher, Institute for Microbiology, Ernst-Moritz-Arndt-University of Greifswald

  • 2006 – 2015
    Independent Group Leader for "Oxidative Stress physiology of bacteria", Institute for Microbiology, Ernst-Moritz-Arndt-University of Greifswald

  • Since 2015
    Full W3-professor for Molecular Microbiology, Institute for Biology- Microbiology, Freie University Berlin

Selected publications

  • Loi VV, Rossius M, Antelmann H. Redox regulation by reversible protein S-thiolation in bacteria. Front Microbiol. 6:187. doi: 10.3389/fmicb.2015.00187.


  • Hillion M, Antelmann H. Thiol-based redox switches in prokaryotes. Biol Chem. 396: 415-44. doi: 10.1515/hsz-2015-0102 (2015)

  • Gaballa A, Chi BK, Roberts AA, Becher D, Hamilton CJ, Antelmann H, Helmann JD. Redox regulation in Bacillus subtilis: The bacilliredoxins BrxA(YphP) and BrxB(YqiW) function in de-bacillithiolation of S-bacillithiolated OhrR and MetE. Antioxid Redox Signal. 21: 357-67. doi: 10.1089/ars.2013.5327. (2014)

  • Chi, B. K., Busche. T., Van Laer, K., Bäsell, K., Becher, D., Clermont, L., Seibold, G., Persicke, M., Kalinowski, J., Messens, J. and Antelmann, H.* Protein S-mycothiolation functions as redox-switch and thiol protection mechanism in Corynebacterium glutamicum under hypochlorite stress. Antioxidants & Redox Signaling 20:589-605, doi:10.1089/ars.2013.5423. (2014)

  • Chi, B.K., Roberts, A., Huyen, T.T.T., Gronau, K., Becher, D., Albrecht, D., Hamilton, C. and Antelmann, H.* S-bacillithiolation protects conserved and essential proteins against hypochlorite stress in Firmicutes bacteria. Antioxidants & Redox Signaling 18: 1273-1295. (2013)

  • Palm, G. J., Chi, B. K., Waack, P.; Gronau, K., Becher, D., Albrecht, D., Hinrichs, W., Read, R.J., Antelmann, H.* Structural insights into the redox-switch mechanism of the MarR/DUF24-type regulator HypR. Nucleic Acids Research; 40: 4178-4192. (2012)

  • Chi, B.K., Gronau, K., Mäder, U., Hessling, B., Becher, D., Antelmann, H.* S-bacillithiolation protects against hypochlorite stress in Bacillus subtilis as revealed by transcriptomics and redox proteomics. Mol. Cell. Proteomics, 10: M111.009506. (2011)

  • Antelmann, H.*, and Helmann, J.D*. Thiol-based redox switches and gene regulation. Forum Review Article on “Redox switches”. Antioxidants & Redox Signaling, 14,1049-1063. (2011)

  • Gaballa, A., Newton, J., Antelmann, H., Parsonage, D., Upton, H., Rawat, M., Claiborne, A., Fahey, R., and Helmann, J.D.* Biosynthesis and functions of Bacillithiol: a major low molecular weight thiol in Bacilli, Proc. Natl. Acad. Sci. 107: 6482-6486. (2010)

  • Antelmann, H., Tjalsma, H., Voigt, B., Ohlmeier, S., Bron, S., van Dijl,*J.M., and Hecker, M. A proteomic view on genome-based signal peptide predictions. Genome Research 11: 14984-14502. (2001)

  • Tjalsma, H., Antelmann, H., Jongbloed, J.D., Braun, P.G., Darmon, E., Dorenbos, R., Dubois, J.Y., Westers, H., Zanen, G., Quax, W.J., Kuipers, O.P., Bron, S., Hecker, M., J. M. van Dijl*. Proteomics of Protein Secretion by Bacillus subtilis: Separating the "Secrets" of the Secretome. Microbiol. Mol. Biol. Rev. 68: 207-233. (2004)

Complete list of publications

Selected projects

  • ERC Consolidator Grant GA No. 615585 MYCOTHIOLOME

  • DFG-SPP1710-project about Thiol-based redox switches and redox sensors in Staphylococcus aureus

  • DFG-GRK1947-project about redox proteomics in Mycobacterium smegmatis

Membership in scientific bodies/juries

  • Associate Editor of "BMC Microbiology"

  • Advisory Editorial Board member of "Molecular Microbiology"

  • Editorial Board member of "Scientific Reports"

  • Review Editor of “Frontiers in Microbiol physiology and Metabolism”

Media coverage



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