Short CV/Education and training

  • 1990
    Abitur (A-levels)

  • 1990 – 1996
    Studied chemistry at the Technical University of Munich, Germany

  • 1996 – 1999
    Doctorate, Institute for Inorganic Chemistry, Technical University of Munich

  • 2000 – 2002
    Postdoctoral research, Institute for Physical Chemistry, University of California, Berkeley, USA

  • 2002 – 2007
    Liebig Fellowship for research at the Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, in the department of NMR-based structural biology

  • Since 2007
    Professor of physical biology, Heinrich Heine University, Düsseldorf, and at the Jülich Research Centre, Germany

Selected publications

  • B. Uluca, T. Viennet, D. Petrović, H. Shaykhalishahi, F. Weirich, A. Gönülalan, B. Strodel, M. Etzkorn, W. Hoyer, H. Heise: DNP-Enhanced solid-state NMR at Cryogenic Temperatures: a Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States. In: Biophys. J. 114, 2018. S. 1614-1623.

  • Y. Ohhashi, Y. Yamaguchi, H. Kurahashi, Y.O. Kamatari, S. Sugiyama, B. Uluca, T. Piechatzek, Y. Komi, T. Shida, H. Müller, S. Hanashima, H. Heise, K. Kuwata, M. Tanaka: Molecular basis for diversification of yeast prion strain conformation. In: Proc. Natl. Acad. Sci. USA, 115, 2018. S. 2389-2394.

  • L. Gremer, D. Schölzel, C. Schenk, E. Reinartz, J. Labahn, R. Ravelli, M. Tusche, C. Lopez-Iglesias, W. Hoyer, H. Heise, D. Willbold & G. Schröder: Fibril structure of amyloid-ß(1-42) by cryo-electron microscopy. In: Science, 358, 2017. S. 116-119.

  • F. Weirich, L. Gremer, E.A. Mirecka, S. Schiefer, W. Hoyer, H. Heise: Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment is Part of the β-sheet Core. In: PLoS ONE 11, 2016. e0161243.

  • T. Viennet, A. Viegas, A. Kupper, S. Arens, V. Gelev, O. Petrov, T. N. Grossmann, H. Heise & M. Etzkorn: Selective protein hyperpolarization in cell lysates using targeted dynamic nuclear polarization. In: Angew. Chem. Int. Ed. Engl. 55, 2016. S.10746-50.

  • Heise, H. et al.: Molecular Level Secondary Structure, Polymorphism and Dynamics of Full-length alpha-Synuclein Fibrils Studied by Solid-State NMR. In: PNAS 102, 2005. S. 15871-15876.

  • Heise, H. et al.: Solid-state NMR investigations on paramagnetic metallocenium salts: Probing intra- and intermolecular spin density distribution. In: J. Am. Chem. Soc. 124, 2002. S. 10823-10832.

  • Heise, H. et al.: Determination of the Spin Distribution in Nitronylnitroxides by Solid-State-NMR Spectroscopy. In: J. Am. Chem. Soc. 121, 1999. S. 9659-9667.

Complete list of publications

Selected projects

  • Investigation of membrane protein interactions using high-resolution solid state NMR spectroscopy

  • Protein misfolding at high resolution using solid state NMR spectroscopy

Membership in scientific bodies/juries

  • Chair of the 38th Discussion meeting of the Magnetic resonance division of the German Chemical Society (GDCh) in Düsseldorf September 2016

  • Ombudsperson for good scientific practice, Heinrich Heine-Universität Düsseldorf

  • Examination Committee for Biochemistry, Heinrich Heine-Universität Düsseldorf

  • Member of the executive committee, GdCh subgroup Magnetic Resonance Spectroscopy (since 2017)


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