Short CV/Education and training

  • Since 2010
    Managing director of the Centre for Molecular Medicine, Goethe University Frankfurt

  • Since 2008
    ECCPS chair (W3) of vascular signalling at Goethe University Frankfurt

  • 2007 – 2008
    Managing director of the Centre for Physiology, Goethe University Frankfurt

  • 2007
    Offer of a C4 professorship (Foundation Chair of Biomedical Sciences) at the University of Hull Medical School, England

  • 2005
    Spokesperson of FG 501 "Vascular homeostasis: molecular mediators and cellular mechanisms"

  • Since 2004
    University professor (C3) of physiology at Goethe University Frankfurt

  • 2003
    Offer of a C4 professorship in molecular medicine at the Technical University of Munich, Germany (declined)

  • 2001
    Appointment as university lecturer (C2)

  • 1999
    Habilitation (postdoctoral qualification) in physiology

  • 1993 – 1999
    Research associate at the Institute of Cardiovascular Physiology, Goethe University Frankfurt, Germany

  • 1991 – 1993
    Postdoc at the Institute of Applied Physiology, University of Freiburg, Germany

  • 1988 – 1991
    Doctoral work at the University of Strasbourg, France. Mark: très honorable

  • 1986 – 1987
    Trainee programme (Gastrointestinal Diseases Project), Beecham Pharmaceuticals Research Division, Harlow, England

  • 1984 – 1988
    Studied pharmacology and biochemistry at Aston University, Birmingham, England. Degree: Bachelor of Science, Combined Honours (First Class)

  • 1977 – 1984
    Cambridge House Girls' Grammar School, Ballymena, Northern Ireland

Selected publications

  • Randriamboavonjy, V. et al.: AMPK {alpha}2 subunit is involved in platelet signaling, clot retraction, and thrombus stability. In: Blood 116, 2010. pp. 2134-2140.

  • Loot, A.E. et al.: Angiotensin II impairs endothelial function via tyrosine phosphorylation of the endothelial nitric oxide synthase. In: J Exp Med 206, 2009. pp. 2889-2896.

  • Randriamboavonjy, V. et al.: Platelet SERCA-2 and µ-calpain activity are altered in type 2 diabetes and restored by rosiglitazone. In: Circulation 117, 2008. pp. 52-60.

  • Fisslthaler, B. et al.: Inhibition of endothelial nitric oxide synthase activity by proline-rich tyrosine kinase 2 in response to fluid shear stress and insulin. In: Circ Res. 102, 2008. pp. 1520-1528.

  • Fisslthaler, B. et al.: Fluid shear stress and NO decrease the activity of the hydroxy-methylglutaryl coenzyme A reductase in endothelial cells via the AMP-activated protein kinase and FoxO1. In: Circ. Res. 100, 2007. e12-e21.

  • Fleming, I. et al.: Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. In: Arterioscler Thromb Vasc Biol. 27, 2007. pp. 2612-2618.

  • Jung, O. et al.: Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension. In: Hypertension 45, 2005. pp. 759-765.

  • Fleming, I. et al.: Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. In: J Cell Sci. 118, 2005. pp. 4103-4111. Highlighted in the editor's choice Sci. Signal. 302, 2005. tw333.

  • Dixit, M. et al.: Gab1, SHP2, and protein kinase A are crucial for the activation of the endothelial NO synthase by fluid shear stress. In: Circ Res. 97, 2005. pp. 1236-1244.

  • Fichtlscherer, S. et al.: Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease. In: Circulation 109, 2004. pp. 178-183.

Selected projects

  • ECCPS Cardio-Pulmonary System

  • SFB 834 "Endothelial Signalling and Vascular Repair"

  • SFB 815 "Redox Regulation: Generator systems and functional consequences"

  • SFB/Transregio 23 "Vascular differentiation and remodelling"

  • European Graduate School GRK 757 "Roles of Eicosanoids in Biology and Medicine"

  • LOEWE Lipid Signalling Research Centre of Frankfurt, Germany (LIFF)

Membership in scientific bodies/juries

  • German National Academy of Sciences Leopoldina, since 2016

  • German Physiological Society (DPG)

  • German Cardiac Society

  • German Society for Microcirculation and Vascular Biology

  • British Pharmacological Society

  • North American Vascular Biology Organisation

  • American Society for Biochemistry and Molecular Biology

  • American Heart Association

Board member:

  • American Journal of Physiology

  • Basic Research in Cardiology

  • British Journal of Pharmacology

  • Journal of Cardiovascular Pharmacology

  • Cons. Editor / Associate Editor:

  • Journal of Vascular Research

  • Cardiovascular Research

  • Circulation Research


You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here


  1. Read what our members say about AcademiaNet.

Follow us

No more excuses!

  1. Please download the brochure "No more excuses" and read more about female experts in Europe, and about AcademiaNet.

Similar profiles

  1. Prof. Dr. Katrin Amunts

    Health, Brain Research

  2. Prof. Dr. Myriam Aouadi

    Health, Obesity, Diabetes, Immunology

  3. Prof. Dr. Silvia Arber

    Biological and related sciences , Health, Neuroscience

  4. Prof. Dr. Wiebke Arlt

    Health, Endocrinology