Short CV/Education and training

  • 1990
    Abitur (A-levels)

  • 1990 – 1995
    Studied biochemistry, Leibniz University Hannover, Medical University Hannover (MHH), University of Veterinary Medicine Hannover

  • 1993
    Research associate, section for structural biology, Max Planck Institute of Biochemistry, Martinsried/Munich, Germany

  • 1994
    Research associate, Department for Molecular and Cell Biology, University of California, Berkeley, CA, USA

  • 1994
    Research associate, Institute of Experimental Immunology, University of Zurich and University Hospital Zurich, Switzerland

  • 1994
    Research associate, Department of Biochemistry, University of Zurich, Switzerland

  • 1995
    Diplom degree in biochemistry, Leibniz University Hannover and Medical University Hannover (MHH)

  • 1995
    Diplom thesis, Department of Biochemistry, University of Zurich, Switzerland

  • 1996 – 2000
    Dissertation, Department of Biochemistry, University of Zurich, and Department for Molecular and Cell Biology, University of California, Berkeley, CA, USA

  • 1997
    Visiting researcher, Department of Biochemistry, University of Montreal, Montreal (Quebec), Canada

  • 1998 – 2000
    Visiting researcher, Department for Molecular and Cell Biology, University of California, Berkeley, USA

  • 2000
    Dissertation in biochemistry (Dr sc. nat.) at the University of Zurich, Switzerland

  • 2000
    Researcher (postdoc), Department of Molecular and Cell Biology, University of California, Berkeley, USA

  • 2000 – 2002
    Researcher (postdoc), Department of Biology II (Biochemistry), University of Freiburg, Germany

  • 2001 – 2002
    Parental leave

  • 2002 – 2003
    European Molecular Biology (EMBO) researcher (postdoc), Department of Biology III - molecular biology and genetics, University of Freiburg

  • 2003 – 2008
    Head of an Emmy Noether junior research group (German Research Foundation (DFG) Excellence Programme) Department of Biology III - molecular biology and genetics, University of Freiburg

  • 2003 – 2004
    Parental leave

  • Since 2007
    BIOSS research group leader, Excellence Cluster Biological Signalling Studies, University of Freiburg

  • Since 2008
    Junior Fellow FRIAS – LIFENET, Freiburg Institute for Advanced Studies (FRIAS), School of Life Sciences (LIFENET), University of Freiburg

  • Since 2010
    Professor of molecular biotechnology, Institute of Biochemistry and Biology, University of Potsdam, Germany

Selected publications

  • Hoffmann, S., Hao, N., Shearwin, K.E., Arndt, K.M. (2019). Characterizing transcriptional interference between converging genes in bacteria. ACS Synth. Biol. doi: 10.1021/acssynbio.8b00477

  • Brechun, K.E., Arndt, K.M.*, Woolley, G.A.* (2019). Selection of Protein-Protein Interactions of Desired Affinities with a Bandpass Circuit. J. Mol. Biol. 431(2), 391-400. *corresponding authors

  • Hoffmann, S.A.; Wohltat, C.; Müller, K.M.; Arndt, K.M. A user-friendly, low-cost turbidostat with versatile growth rate estimation. PLoS One 12(7): e0181923.

  • Hoffmann, S.A., Kruse, S.M. & Arndt, K.M. (2016). Long-range transcriptional interference in E. coli used to construct a dual positive selection system for genetic switches. Nucleic Acids Res. 44(10): e95.

  • Mazumder, M., Brechun, K.E., Kim, Y.B., Hoffmann, S.A., Chen, Y.Y., Keiski, C.L., Arndt, K.M., McMillen, D.R., Woolley, G.A. (2015). An Escherichia coli system for evolving improved light-controlled DNA-binding proteins. Protein Eng. Des. Sel., 1-10.

  • Azuma Y., Kükenshöner, T., Ma, G. Yasunaga, J., Imanishi, M., Tanaka, G., Nakase, I., Maruno, T., Kobayashi, Y., Arndt, K.M.*, Matsuoka, M.* & Futaki, S.* (2014). Controlling leucine-zipper partner recognition in cells through modification of a-g interactions. Chem. Commun. (Camb.) 50(48), 6364-6367. *corresponding authors

  • Hagen, S., Baumann, T., Wagner, H.J., Morath, V., Kaufmann, B., Fischer, A., Bergmann, S., Schindler, P., Arndt, K.M.* & Müller, K.M.* (2014). Modular adeno-associated virus (rAAV) vectors used for cellular virus-directed enzyme prodrug therapy. Nature Scientific Reports 4, 3759. * corresponding authors.

  • Zhang, F., Timm, K.A., Arndt, K.M.* & Woolley, G.A.* (2010). Photo-control of Coiled-coil Proteins in Living Cells. Angew. Chem. Int. Ed. 49(23), 3943-3946. * corresponding authors

  • Mason, J.M., Hagemann, U.B., Arndt, K.M.: Role of Hydrophobic and Electrostatic Interactions in Coiled Coil Stability and Specificity. In: Biochemistry 48(43), 2009. pp. 10380-10388.

  • Jouaux, E.M. et al.: Improving the Interaction of Myc-Interfering Peptides with Myc Using Molecular Dynamics Simulations. In: J. Pept. Sci. 15(1), 2009. pp. 5-15.

Complete list of publications

Selected projects

  • Photo-controlled transcription factors for probing how mice form memories; collaborative research project funded by the Human Frontier Science Program (HFSP)

  • The role of transcription factors in tumour cell invasion: AP-1 and Myc inhibitors for interfering with tumour growth and metastasis; Sub-project C1 in the Collaborative Research Centre SFB 850: Control of cell motility during morphogenesis, tumour invasion and metastasis

  • Analysis and programming of transmembrane signalling by nanoscale patterns: Modified DNA origami as input for B- and T-cells; Project in the Excellence Cluster BIOSS (Centre for Biological Signalling Studies)

Additional qualifications

  • Junior Fellow, Freiburg Institute for Advanced Studies, Freiburg, Germany, 2008 – 2011

  • Emmy Noether group leader (instead of Habilitation (postdoctoral qualification)), 2003 – 2008

Soft Skills/Other activities and achievements

Soft Skills

  • Baden-Württemberg Ministerial Certificate for the acquisition of competence in university teaching

  • Participation in project management and personnel management seminars

Other activities and achievements/family

  • Four children

  • Parental leave: 02/2001 – 07/2002 and 07/2003 – 12/2004


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