Prof. Dr. Kerstin Bartscherer

• 1998 – 2002
  Studied biotechnology at Hochschule Mannheim – University of Applied Sciences (B.Sc.)
  
  

• 2002 – 2004
  Studied molecular biology at the University of Göttingen /International Max Planck Research School, Germany (M.Sc.)
  
  

• 2004 – 2007
  Doctorate from Heidelberg University / German Cancer Research Centre (DKFZ), under Prof. Michael Boutros
  
  

• 2007 – 2008
  Postdoc in the Department de Genetica under Prof. Emili Salo at Universidad de Barcelona,Spain, and at the German Cancer Research Centre (DKFZ), Heidelberg, under Prof. Boutros
  
  

• 2009 – 2010
  Team leader at the Centre for Biotechnology and Medical Technology, Faculty of Medicine, Mannheim / Heidelberg University
  
  

• 2010 – 2019
  Research group leader at the Max Planck Institute for Molecular Biomedicine, Münster, Germany
  
  

• 2016
  Awardee of an ERC Starting Grant
  
  

• Since 2018
  Research group leader at the Hubrecht Institute for Developmental Biology and Stem Cell Research, Utrecht, The Netherlands
  
  

• Since 2021
  Full professor at Osnabrück University, Osnabrück, Germany
  
  

• Schmidt D, Reuter H, Hüttner K, Ruhe L, Rabert F, Seebeck F, Irimia M, Solana J, and Bartscherer K (2018). The Integrator complex regulates differential snRNA processing and fate of adult stem cells in the highly regenerative planarian Schmidtea mediterranea. PLoS Genet 14:e1007828.

• Owlarn S, Klenner F, Schmidt D, Rabert F, Tomasso A, Reuter H, Mulaw MA, Moritz S, Gentile L, Weidinger G, and Bartscherer K (2017). Generic wound signals initiate regeneration in missing-tissue contexts. Nature Commun 8: 2282.

• Seebeck F, März M, Reuter H, Vogg MC, Mildner K, Zeuschner D, Rabert F, and Bartscherer K (2017). Integrins are required for tissue organization and restriction of neurogenesis in regenerating planarians. Development, 144, 795-807.

• Owlarn S, and Bartscherer K (2016). Go ahead, grow a head! A planarian’s guide to anterior regeneration. Regeneration 3, 139-155.

• Reuter H, März M, Vogg MC, Eccles D, Grifol-Boldu L, Owlarn S, Wehner D, Adell T, Weidinger G, and Bartscherer K (2015). -catenin-dependent control of positional information along the AP body axis in planarians involves a Teashirt family member. Cell Rep 10, 253-265.

• Hjeij R, Onoufriadis A, Watson CM, Slagle CE, Klena N, Dougherty GW, Kurkowiak M, Loges NT,1 Diggle CP, Morante NFC, Gabriel G, Lemke KL, Li Y, Pennekamp P, Menchen T, Konert F, Marthin JK, Mans DA, Letteboer SJF, Werner C, Burgoyne T, Westermann C, Rutman A, Carr IM, O'Callaghan C, Moya E, Chung EMK, UK10K, Sheridan E, Nielsen KG, Roepman R, Bartscherer K, Burdine RD, Lo CW, Omran H, Mitchison HM (2014). CCDC151 mutations cause Primary Ciliary Dyskinesia by disruption of the Outer Dynein Arm docking complex formation. Am J Hum Genet 95, 257-274.

• Almuedo-Castillo M, Crespo X, Seebeck F, Bartscherer K, Salo E, Adell T (2014). JNK controls the onset of mitosis in planarian stem cells and triggers apoptotic cell death required for regeneration and remodeling. PLoS Genetics 10, e1004400.

• Vogg MC, Owlarn S, Perez Rico YA, Xie J, Suzuki Y, Gentile L, Wu W, and Bartscherer K (2014). Stem cell-dependent formation of a functional anterior regeneration pole in planarians requires Zic and Forkhead transcription factors. Dev Biol 390, 136-148.

• Böser A, Drexler HCA, Reuter H, Schmitz H, Wu G, Schöler HR, Gentile L, and Bartscherer K (2013). SILAC proteomics of planarians identifies Ncoa5 as a conserved component of pluripotent stem cells. Cell Rep 5, 1142-1155.

• März, M., Seebeck, F., and Bartscherer, K. (2013). A Pitx transcription factor controls establishment and maintenance of the serotonergic lineage in planarians. Development 140, 4499-4509.

• Gross J.C., Chaudhary, V., Bartscherer, K., and Boutros, M. (2012). Active Wnt proteins are secreted on exosomes. Nature Cell Biol 14, 1036-45.

• Sandmann, T., Vogg, M.C., Owlarn, S., Boutros, M., and Bartscherer, K. (2011). The head regeneration transcriptome of the planarian Schmidtea mediterranea. Genome Biol 12(8):R76.

• Gentile, L., Cebrià, F., and Bartscherer, K. (2011). The planarian flatworm: a model for stem cell biology and nervous system regeneration. Dis Model Mech 4, 12-9.

• Buechling, T., Bartscherer, K., Ohkawara, B., Chaudhary, V., Spirohn, K., Niehrs, N., and Boutros, M. (2010). Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol 20, 1263-1268.

• Adell, T., Saló, E., Boutros, M., and Bartscherer, K. (2009). Smed-Evi/Wntless is required for beta-catenin-dependent and -independent processes during planarian regeneration. Development 136, 905-910.

• Davidson, G., Shen, J., Huang, Y., Su, Y., Karaulanov, E., Bartscherer, K., Hassler, C., Stannek P., Boutros, M., and Niehrs, C. (2009). Cell Cycle Control of Wnt Receptor Activation. Dev Cell 17, 788-799.

• Bartscherer, K., Pelte, N., Ingelfinger, D., and Boutros, M. (2006). Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125, 523-533.

• Tissue regeneration

• https://www.youtube.com/watch?v=HBLcsCnceOs

Other activities and achievements/family

• three children

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