Short CV/Education and training

  • Prof. Laura M. Lechuga is Full Professor of the Spanish National Research Council (CSIC) and Head of the Nanobiosensors and Bioanalytical Applications Group at the Catalan Institute of Nanoscience and Nanotechnology (ICN2) in Barcelona (Spain) and at the Networking Biomedical Research Center (CIBER-BBN).

  • The principal focus of her research is the development of novel nanobiosensor devices based on nanoplasmonics and silicon-based photonics principles for point-of-care diagnostics. Prof. Lechuga has been at the forefront of the Photonic Biosensor area during more than eighteen years, making key contributions and opening new horizons in this field. Her research activities have encompassed from fundamental research to the technological operation of complete sensing platforms, including the technological transfer into products of social applicability. Her Group is considered as a world reference in this field.

  • She has published over 260 articles, book chapters and proceedings, has 8 families of patents, and has presented her work worldwide in more than 365 invited talks. She has co-founded two spin-offs companies.

  • In 2020, during the COVID-19 outbreak and pandemic, she has been included in the Expert Scientific Panel advising the Ministry of Science and Innovation and the Spanish Government in the management of the pandemic. She is also the coordinator of one of the first EU funded projects for COVID-19 Diagnostics.

Selected publications

  • G.A. López-Muñoz, M.C. Estevez, E.C. Peláez-Gutierrez, A. Homs-Corbera, M.C. García-Hernandez, J. Ignacio Imbaud and L.M. Lechuga. A Label-free Nanostructured Plasmonic Biosensor based on Blu-ray Discs with integrated microfluidics for sensitive biodetection. Biosens. & Bioelec. 96, 260–267. https://doi.org/10.1016/j.bios.2017.05.020 (2017)

  • C. Szydzik, A.F. Gavela, S. Herranz, J. Roccisano, M. Knoerzer, P. Thurgood, K. Khoshmanesh, A. Mitchell, and L.M. Lechuga. An automated integrated optofluidic biosensor platform combining bimodal waveguide interferometric sensors and injection moulded microfluidics. Lab on a Chip 17, 2793 – 2804. https://doi.org/10.1039/C7LC00524E (2017)

  • P. Ramirez-Priego, D. Martens, A.A. Elamin, P. Soetaert, W. Van Roy, R. Vos, B. Anton, R. Bockstaele, H. Becker, M. Singh, P. Bienstman and L.M. Lechuga. Label-free and real-time detection of tuberculosis in human urine samples using a nanophotonic point-of-care platform. ACS Sensors 3, 10, 2079-2086. https://doi.org/10.1021/acssensors.8b00393 (2018)

  • E-C. Peláez, M.-Carmen Estévez, A. Portela, J.-P. Salvador, M.-P. Marco and L.M. Lechuga. Nanoplasmonic biosensor device for the monitoring of Acenocoumarol Therapeutic Drug in Plasma. Biosens. Bioelect. 119, 149-155. https://doi.org/10.1016/j.bios.2018.08.011 (2018)

  • P. Dey, N. Fabri-Faja, O. Calvo, R. Terborg, F. Yesilkoy, A. Fàbrega, J.C. Ruiz-Rodriguez, J.J. González-López, M.- C. Estévez, H. Altug, V. Pruneri and L.M. Lechuga. Label-free bacteria quantification in blood plasma by a bioprinted microarray based interferometric Point-of-care device. ACS Sensors. 4 (1), 52–60. https://doi.org/10.1021/acssensors.8b00789 (2018)

  • Huertas, C.; Bonnal, S.; Soler, M.; Medina Escuela, A.; Valcarcel, J.; Lechuga, LM. Site-specific mRNA cleavage for selective and quantitative profiling of alternative splicing with label-free optical biosensors. Analytical Chemistry 91 (23), 15138-46. https://doi.org/10.1021/acs.analchem.9b03898 (2019)

  • N. Fabri-Faja, O. Calvo-Lozano, P. Dey, R. A. Terborg, M.-C. Estévez, F. Yesilköy, J. Pello, H. Altug, V. Pruneri, L.M. Lechuga. Detection of protein and miRNA biomarkers for early Sepsis diagnosis with an optical Point-of-care microarray biosensor. Ana. Clinica Acta, 1077, 232-242 doi.org/10.1016/j.aca.2019.05.038 (2019)

  • Maldonado, M.-C. Estévez, A. Fernández Gavela, J.J. González-López, A.B. González-Guerrero and L.M. Lechuga. Label-free detection of few number of nosocomial bacteria using a nanophotonic interferometric biosensor. Analyst 145, 497-506. https://doi.org/10.1039/C9AN01485C (2020)

  • E.C. Peláez, M.C. Estévez, A. Mongui, M.C. Menendez, C. Toro, O. Herrera-Sandoval, J. Robledo, M.J. Garcia, P. del Portillo, and L.M. Lechuga. Detection and quantification of HspX antigen in sputum samples using plasmonic biosensing: toward a real Point-of-Care (POC) for tuberculosis diagnosis. ACS Infections Diseases. 6, 5, 1110–1120. https://doi.org/10.1021/acsinfecdis.9b00502 (2020)

  • M. Soler, M.-C. Estevez, M.C. Cardenosa-Rubio, A. Astúa, and L.M. Lechuga. How nanophotonic label-free biosensors can contribute to rapid and massive diagnostics of respiratory virus infections: COVID19 case. ACS Sensors 5 (9), 2663-2678. https://doi.org/10.1021/acssensors.0c01180 (2020)



Complete list of publications

Selected projects

  • Plataformas nanoplasmonicas point-of-care como sistema innovador de diagnóstico y seguimiento de terapias (PREDICT). Programa de Tecnología Electrónica y Comunicaciones PN de I+D+i. TEC2016-78515-R, 2017 – 2019

  • Scalable, point-of-care and label free microarray platform for rapid detection of Sepsis (RAIS) H2020-ICT-2014-1-644956, 2015 – 2018

  • Development of a low-cost point-of-care test for Tuberculosis detection (POCKET), FP7-ICT-2013-10-610389. ICT-10-3.3-Heterogeneous Integration and take-up of Key Enabling Technologies for Components and Systems, 2013 – 2017

  • Biosensors,Reporters and Algal Autonomous Vessels for Ocean operation (BRAAVOO). FP7-OCEAN-201-614010., 2013 – 2016

  • Lab-on-a-chip integration of biophotonic devices to study gene expression alterations in cellular pathways (EPISENS). Programa de Tecnología Electrónica y Comunicaciones. PN de I+D+i. TEC2012-34280, 2013 – 2016

Membership in scientific bodies/juries

  • Member of Scientific Advisory Boards: Spanish Foundation for Science and Technology (FECYT), 2004 – 2005, Andalucian Center in Nanomedicine and Biotechnology (BIONAND) Málaga (Spain), since 2014, Biomedical Institute of the University of Vigo (Spain) since its foundation, Micro and Nano Research Facility (RMIT University, Melbourne, Australia) since 2016, Centro Investigaciones en Óptica (CIO) CONACYT (México), since 2016

  • Founder and Coordinator of the National Network on Biosensor Devices (2007); Co-Founder and Secretary of the Spanish Technological Platform on Nanomedicine, since 2006

  • Advisory Expert for public Foundations and organizations (OPTI, COTEC, Joint Research Centres-UE,..); private Foundations (Bankinter Future Trends; Vodafone Foundation, M. Botín Foundation)

  • Regular participation in international selection committees (private foundations and public universities)

  • External expert evaluator for prizes as the Gottfried Wilhelm Leibniz Prize, Deutsche Forschungsgemeinschaft (DFG), Germany (2016); Emergent Talent SRUK/CERU 2017, FUNCAS prize to the best Spanish Doctoral Thesis (2017), Prize Fundación BBVA-RSEF (2017) and others

  • External expert collaborator for the Spanish National Scientific & Technological Program 2017 – 2020 (Spanish Government)

  • Participation in high level evaluation panels for national and international worldwide agencies. More than 40 panel evaluation/high expert panels for the 5th, 6th, 7th and H2020 (including Advanced ERC) EU programs

Media coverage

  • Regular participation in TV, radio programs, press interviews, social media (more than 200 activities)

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