Prof. Avan Aihie Sayer
HealthAcademic Medicine
Health
Systemic neuroscience
How is information processed and encoded in the brain's neural networks in order to realize learning, memory and behaviour? This is one of the most fundamental questions of the modern life sciences, and one that my working group and I would like to answer.
1. To determine the cellular and synaptic mechanisms underlying communication between nerve cells in the brain.
2. To investigate how those brain rhythms are generated which are assumed to serve the purpose of processing and encoding information.
3. To determine the rules governing synaptic plasticity in nerve cells as a basis of information storage.
4. To clarify the role of the different types of nerve cells in behaviour and memory formation.
Fellowship from the Friedrich Ebert Foundation
Young Investigators Prize from the International Society for Neuroethology
Lichtenberg Award
Offer of a W2 professorship in the Institute of Physiology at Marburg University, Germany, declined
Czech, English, German
Murray AJ, Sauer J, Mcclure CJ, Cheyne LA, Riedel G, Bartos M, Wisden W, Wulff P (2011): Parvalbumin-positive hippocamapl interneurons are required for spatial working but not reference memory Nat Neurosci (Epup ahead of print).
Bartos M, Alle H, Vida I (2010): Role of microcircuit structure and input integration in hippocampal interneuron recruitment and plasticity. Neuropharmacology (Epub ahead of print).
Sambandan S, Sauer J, Vida I, Bartos M (2010): Associative plasticity at excitatory synapses of fast-spiking interneurons in the dentate gyrus. J Neurosci 30:11826-11837.
Sauer J, Bartos M (2010): Recruitment of early postnatal parvalbumin-positive hippocampal interneurons by GABAergic excitation. J Neurosci 20:110-115.
Doischer, D, Hosp, P, Yanagawa, Y, Obata, K, Jonas, P, Vida, I, Bartos, M (2008): Postnatal development of hippocampal basket cells from slow to fast signaling devices. J Neurosci 26:12956-12968.
Bartos M, Vida I, Jonas P (2007): Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci 8:45-56.
Vida I, Bartos M, Jonas P (2006): Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron 49:107-117 (equal contribution of the authors).
Disc1 schizophrenia model
Mechanisms of synaptic plasticity
Theoretical neural networks of the hippocampus
Synaptic communication between nerve cells
Imaging techniques for displaying the spread of activity in biological neural networks
Reviewer for international journals such as Science, The Journal of Neuroscience and Neuron
Referee for various international research programmes, such as Human Frontier Science Program (HFSP), Welcome Trust, National Institutes of Health (USA, Canada)
Society of Neuroscience
German Physiological Society (DPG)
Equal opportunity liaison for the Faculty of Medicine, University of Freiburg, Germany
Higher education association
Member of the Neurex advisory board (Neuroscience upper Rhine network)
2 years of parental leave, family with 2 children
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