Short CV/Education and training

Academic education:

  • 1995 – 1998
    B.S. Biological Sciences, Faculty of Science, Charles University, Prague, Czech Republic

Scientific degrees:

  • 1998 – 2000
    M.S. Genetics and Molecular biology, Department of Genetics and Microbiology, Charles University, Prague, Czech Republic

  • 2000 – 2004
    Ph.D. Cell and Molecular Biology, Faculty of Biological Sciences, University of South Bohemia, Ceske Budejovice, Czech Republic

Scientific career:

  • 2000 – 2004
    Graduate student, Department of Molecular Biology, University of South Bohemia, Czech Republic (Supervised by Dr. Marek Jindra)

  • 2003
    NATO Fellow, Arthropod-Borne and Infectious Diseases Laboratory (AIDL), Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA

  • 2004
    Postdoctoral research associate, Department of Genetics, Institute of Entomology ASCR, Ceske Budejovice, Czech Republic (Supervised by Dr. Marek Jindra)

  • 2004 – 2007
    Postdoctoral Fellow, Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA (Supervised by Dr. Dirk Bohmann)

  • 2007 – 2008
    Research Assistant Professor, Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY, USA

  • 2008 – 2013
    Independent Junior Research Group Leader, CECAD, University of Cologne, Institute for Genetics, Cologne, Germany

  • Since 2013
    Professor "Signaling networks in development and disease", Cologne Excellence Cluster for Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne

Selected publications

  • Claudius AK, Romani P, Lamkemeyer T, Jindra M, Uhlirova M. (2014) Unexpected role of the steroid-deficiency protein Ecdysoneless in pre-mRNA splicing. PLoS Genet, 10: e1004287.

  • Külshammer E, Uhlirova M (2013) The actin cross-linker Filamin/Cheerio mediates tumor malignancy downstream of JNK signaling. J Cell Sci, 126, 927 – 938.

  • Rynes J, Donohoe CD, Frommolt P, Brodesser S, Jindra M, Uhlirova M (2012) Activating transcription factor 3 regulates immune and metabolic homeostasis. Mol Cell Biol 32: 3949 – 3962.

  • Sekyrova P, Bohmann D, Jindra M, Uhlirova M (2010) Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis. Development 137: 141 – 150.

  • Wang Q, Uhlirova M, Bohmann D (2010) Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis. Dev Cell 18: 157 – 164.

  • Uhlirova M, Bohmann D (2006) JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila. EMBO J 25: 5294 – 5304.

  • Uhlirova M, Jasper H, Bohmann D (2005) Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model. Proc Natl Acad Sci USA 102: 13123 – 13128.

Complete list of publications

Selected projects

  • Oncogene cooperation in Drosophila tumor model

  • Stress signaling and homeostasis

  • Regulation of epithelial morphogenesis

Media coverage

Soft Skills/Other activities and achievements

Additional interests

  • Mentoring


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