Short CV/Education and training

  • Since 2018
    Vice President for Research and Academic Infrastructure, Goethe-University Frankfurt

  • Since 2010
    W3 professorship and director of the Institute of Experimental Tumour Research in Paediatrics, Goethe University Frankfurt, Germany

  • 2007 – 2010
    DFG W3 research professorship in paediatrics research, Ulm University

  • 2002 – 2007
    Heisenberg Fellowship from the German Research Foundation (DFG)

  • 2001
    Habilitation (postdoctoral qualification) and venia legendi (authorisation to teach) in the field of paediatrics in the Faculty of Medicine, Ulm University

  • 2001
    Specialist examination in paediatrics

  • 1998
    Postdoc at Institute Gustave Roussy, Villejuif, France

  • 1997 – 2001
    Junior doctor at the University Children's Hospitals of Heidelberg and Ulm, Germany

  • 1996 – 1997
    Postdoc at the German Cancer Research Centre (DKFZ)

  • 1995 – 1996
    Foundation year at the University Children's Hospital, Heidelberg, Germany

  • 1995
    United States Medical Licensing Examinations I & II

  • 1988 – 1995
    Studied medicine at the University of Cologne; Harvard Medical School, Boston, USA; University of California, San Francisco, USA; University of Arizona, Phoenix, USA; University College Dublin, Ireland

  • 1987
    Abitur (A-levels), Gymnasium (grammar school), Cologne, Germany

Selected publications

  • Dolgikh N, Hugle M, Vogler M, Fulda S. NRAS-mutated rhabdomyosarcoma cells are vulnerable to mitochondrial apoptosis induced by co-inhibition of MEK and PI3K. Cancer Res. 2018. Feb 6 [E-pub ahead of print].

  • Rohde K, Kleinesudeik L, Roesler S, Loewe O, Heidler J, Schroeder K, Wittig I, Droese S, Fulda S. A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis. Cell Death Differ. 24, 83-97, 2017.

  • Safferthal C, Rohde K, Fulda S. Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells. Oncogene 36, 1487-1502, 2017.

  • Schenk B, Fulda S. Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death. Oncogene. 34, 5796-5806, 2015.

  • Hugle M, Belz K, Fulda S. Identification of synthetic lethality of PLK 1 inhibition and microtubule-destabilizing drugs. Cell Death Differ. 22, 1946-56, 2015.

  • Schoeneberger H, Belz K, Schenk B, Fulda S. Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death. Oncogene. 34, 4032-43, 2015.

  • Belz K, Schoeneberger H, Wehner S, Weigert A, Bönig H, Klingebiel T, Fichtner I, Fulda S. Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly. Blood 124, 240-50, 2014.

  • Basit F, Cristofanon S, Fulda S. Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes. Cell Death Differ. 20, 1161-73, 2013.

  • Loeder S, Fakler M, Schoeneberger H, Cristofanon S, Leibacher J, Vanlangenakker N, Bertrand MJM, Vandenabeele P, Jeremias I, Debatin KM, Fulda S. RIP is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis. Leukemia, 26, 1020-9, 2012.

  • Fulda S, Wick W, Weller M., Debatin, K.-M. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med, 8, 808-815, 2002.

Complete list of publications

Selected projects

  • Coordinator Else Kröner-Forschungskolleg Frankfurt "Zielgerichtete Therapiestrategien in der Onkologie"

  • Coordinator Collaborative Research Project "Targeting the hedgehog pathway in pediatric cancers", German Cancer Aid

  • Member Steering Committee DFG Collaborative Research Center 1177 "Molecular and Functional Characterization of Selective Autophagy"

  • Director of the EU Seventh Framework Programme (FP7) project: Systems biology of apoptosis in cancer and AIDS

  • Director of EU project IAP6/18: Signal transduction in inflammation: from gene to organism

  • Director of the BMBF (German Federal Ministry of Education and Research) project: TranSaRNet – Translational sarcoma network

  • Director of German Research Foundation (DFG) Clinical Research Unit 167: Regulation of apoptosis and its dysfunction in human diseases, since 2006

  • Director of the Marie Curie Research Training Network: ApopTrain (European Commission, Sixth Framework Programme – FP6), since 2006

  • Director of the BMBF network: Apoptosis as a target in tumour therapy, within the framework of the funding programme "Innovative therapies on a molecular and cellular basis", since 2006

Membership in scientific bodies/juries

  • German National Academy of Sciences Leopoldina

  • German Council of Science and Humanities

  • Hochschulrat Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen

  • Wissenschaftlicher Beirat Mercator Research Center Ruhr

  • Auswahlausschuss für die Vergabe von Humboldt-Forschungsstipendien, Alexander von Humboldt-Stiftung

  • Wissenschaftlicher Beirat Paul-Ehrlich-Institut

  • DFG Senatskommission für Grundsatzfragen in der Klinischen Forschung (SGKF)

  • Forschungsrat, Goethe-Universität Frankfurt

  • Senat, Goethe-Universität Frankfurt

  • Expertenkommission des Österreichischen Wissenschaftsrats zur Evaluation der Klinischen Forschung in Österreich

  • DFG Auswahlausschuss Deutsch-Israelische Projektkooperation (DIP)

  • Deutsche Krebshilfe Fachausschuss "Klinische Forschung, kliniknahe Grundlagenforschung"

  • European Association for Cancer Research (EACR)

  • American Association for Cancer Research (AACR)

  • American Association for the Advancement of Science (AAAS)

  • Women in Cancer Research (WIOS)

  • European Cell Death Organization (ECDO)

  • International Cell Death Society (ICDS)

  • Deutsche Gesellschaft für Kinderheilkunde (DGKJ)

  • Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH)

  • German Society for Hematology/Oncology (DGHO)

  • Internationale Gesellschaft für pädiatrische Onkologie (SIOP)

  • Deutscher Hochschulverband (DHV)

Additional qualifications

  • "Leadership and Responsibility" professional development certificate from the Württemberg Management and Business Academy, 2007

  • Coaching as a Leadership Role: professional development seminar, 2007

  • Baden-Württemberg certificate of higher-education pedagogy (200 hours of instruction), 2005


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