Dr. Chantal Abergel
Biological and related sciences, Physical sciences, Environmental virology, Molecular and structural biology, biochemistry
BIOSS – Center for Biological Signalling Studies
SGBM – Spemann Graduate School of Biology and Medicine
Biological and related sciences, Physical sciences
Biochemistry and biophysics
Structural biology (protein X-ray crystallography), Membrane proteins, Transporters and Channels, Metalloproteins, Proteoliposomes, Planar lipid membranes, Electrophysiology, Spectroscopy
Emmy Noether fellowship from the German Research Foundation (DFG), since 2006
Marie Curie Intra-European Fellowship (IEF-FP6), 2004 – 2005
PhD fellowship: Portuguese Science and Technology Foundation (FCT), 1998 – 2002
Young researcher scholarship: National Scientific and Technological Research Council (J.N.I.C.T.), 1996 – 1997
Undergraduate research award: PRODEP/95 (Action 5.2), 1995
English, German, Portuguese
Helfmann, S. et al.: Cooperative binding of ATP and ADP in the trimeric PII protein GlnK2 from Archaeoglobus fulgidus. In: J. Molec. Biol. 402(1), 2010. pp. 165-177.
Loqué, D. et al.: Pore Mutations in Ammonium Transporter Amt1 with Increased Electrogenic Ammonium Transport Activity. In: J. Biol. Chem. 284(37), 2009. pp. 24988-24995.
Andrade, S.L.A. et al.: Crystal Structure of the NADH:quinone oxidoreductase WrbA from Escherichia coli. In: J. Bacteriol. 189, 2007. pp. 9101-9106.
Andrade, S.L.A., Einsle, O.: The Amt/Mep/Rh Family of Ammonium Transport Proteins. In: Molec. Memb. Biol. 24, 2007. pp. 357-365.
Einsle, O. et al.: Assignment of Individual Metal Redox States in a Metalloprotein by Crystallographic Refinement at Multiple X-ray Wavelengths. In: J. Am. Chem. Soc. 129, 2007. pp. 2210-2211.
Andrade, S.L.A. et al.: Crystal Structure of the Archaeal Ammonium Transporter Amt-1 from Archaeoglobus fulgidus. In: Proc. Natl. Acad. Sci. USA 102, 2005. pp. 14994-14999.
Andrade, S.L.A. et al.: Structures of the Iron-Sulfur Flavoproteins from Methanosarcina thermophila and Archaeoglobus fulgidus. In: J. Bacteriology 187, 2005. pp. 3848-3854.
Andrade, S.L.A. et al.: Kinetic behavior of Desulfovibrio gigas Aldehyde Oxidoreductase encapsulated in Reverse Micelles. In: Biochem. Biophys. Res. Comm. 308, 2003. pp. 73-78.
Einsle, O. et al.: The Nitrogenase MoFe Protein at 1.16 Å Resolution: A Central Ligand in the FeMo Cofactor. In: Science 297, 2002. pp. 1696-1700.
Andrade, S.L.A. et al.: Aldehyde oxidoreductase Activity in Desulfovibrio alaskensis NCIMB 13491 – EPR Structural Assignment of the [2Fe-2S] Cluster to the Mo site. In: Eur. J. Biochem 267, 2000. pp. 2054-2061.
Ammonium transport across prokaryotic and eukaryotic membranes: Structure and function of Amt proteins
German Research Foundation/Deutsche Forschungsgemeinschaft (DFG)
Research Council for Biosciences and Environment (RCBE), Academy of Finland
MAX INF workshop on experimental phasing of macromolecules, University of Göttingen, Germany, 2006.
Course on membrane proteins: the rocky road from gene to structure, Instituto de Tecnologia Química e Biologica (ITQB), Oeiras, Portugal, 2005.
"RapiData2005" – Rapid Data Collection and Structure Solving at the NSLS: A practical course in macromolecular X-ray diffraction measurement, Biology Department and National Synchrotron Light Source Brookhaven National Laboratory, New York, USA, 2005.
MAX INF workshop on methods in crystallography, University of Göttingen, 2003.
Course on molecular structure determination by X-Ray diffraction, Faculty of Sciences and Technology, Universidade Nova de Lisboa, Lisbon, Portugal, 2001.
Course on electron paramagnetic resonance – principles and applications to biology, Advanced Studies Centre of Coimbra, Department of Neurosciences, University of Coimbra, Coimbra, Portugal, 2000.
EU-ESF advanced practical training course on chemistry of metals in biological systems, Catholic University of Louvain-la-Neuve, Belgium, 1998.
Course on X-Ray crystallography and NMR of metalloproteins, Technical Institute of Lisbon, 1998.
Research
1 daughter, parental leave (50 %), 2009
German language course: EUROCENTER – Language Institute, Lisbon, Portugal, 1986 – 1988
First Certificate in English: Cambridge Institute, Lisbon 1985
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Biological and related sciences, Physical sciences, Environmental virology, Molecular and structural biology, biochemistry
Biological and related sciences, Health, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology
Biological and related sciences, Microbial bioelectrochemistry, Microbial electrophysiology
Biological and related sciences, Environment, Plant Ecology, Conservation Biology, Landscape Genomics
Do these proteins carry the gas ammonia or the ammonium ion across cell membranes? Biochemists have long speculated about the details of the ammonium transport proteins (Amt), which include the Rhesus protein factors. Researchers from Freiburg, Germany were able to show experimentally that indeed the ion is carried across the membrane, not the gas.