Short CV/Education and training

  • 1985
    PhD Computational Molecular Biology

  • 1977
    MSc Genetics (with distinction)

  • 1974
    BSc Mathematics and Biology

Selected publications

  • Altuvia, Y., Schueler, O., and Margalit, H. (1995) Ranking of potential binding peptides to MHC molecules by a computational threading approach. J. Mol. Biol., 49: 244-250.

  • Mandel-Gutfreund, Y., Schueler, O., and Margalit, H. (1995) Comprehensive analysis of hydrogen in regulatory protein-DNA complexes: In search of common principles. J. Mol. Biol. 253: 370-382.

  • Argaman, L., Hershberg, R., Vogel, J., Bejerano, G., Wagner, E.G.H.*, Margalit, H.*, and Altuvia, S.* (2001) Novel Small RNA-encoding genes in the intergenic regions of Escherichia coli. Curr Biol. 11: 941-950. (* Corresponding author)

  • Sprinzak E. and Margalit H. (2001) Correlated sequence-signatures as markers of protein-protein interaction. J. Mol. Biol. 311: 681-692.

  • 5. Yeger-Lotem, E., Sattath, S., Kashtan, N., Itzkovitz, S., Milo, R., Pinter, R.Y., Alon, U., and Margalit, H. (2004) Network motifs in integrated cellular networks of transcription regulation and protein-protein interaction. Proc. Natl. Acad. Sci. USA. 101: 5934-5939.

  • Stern-Ginossar, N.*, Elefant, N.*, Zimmermann, A., Wolf, D.G., Saleh, N., Biton, M., Horwitz, E., Prokocimer, Z., Prichard, M., Hahn, G., Goldman-Wohl, D., Greenfield, C., Yagel, S., Hengel, H., Altuvia, Y., Margalit, H.#, Mandelboim, O. #. (2007) Host immune system gene targeting by a viral miRNA. Science 317: 376-381. (# Corresponding authors, equal contribution)

  • Shimoni, Y., Friedlander, G., Hezroni, G., Niv, G., Altuvia, S., Biham, O.*, and Margalit, H.*(2007) Regulation of gene expression by small non-coding RNAs: A quantitative view. Mol. Syst. Biol. 3: 138. * Corresponding author)

  • Melamed, S., Peer, A., Faigenbaum-Romm, R., Gatt, Y.E., Reiss, N., Bar, A., Altuvia, Y., Argaman, L. and Margalit, H. (2016) Global mapping of small RNA-target interactions in bacteria. Mol. Cell 63: 884-897.

  • Nitzan, M., Rehani, R. and Margalit, H. (2017) Integration of bacterial small RNAs in regulatory networks. Ann. Rev. Biophys. 46:131-148.

  • Pearl Mizrahi, S., Elbaz, N., Argaman, L., Altuvia, A., Katsowich, N., Socol, Y., Bar, A., Rosenshine, I.*, and Margalit, H.* (2021) The impact of Hfq-mediated sRNA-mRNA interactome on the virulence of enteropathogenic Escherichia coli. Science Advances. eabi8228.

Complete list of publications

Membership in scientific bodies/juries

  • Scientific Advisory Board, Helmholtz-Institute for RNA-based Infection Research (HIRI), Wurzburg, Germany, since 2021

  • Scientific Advisory Board, Max Planck Institute for Molecular Genetics, Berlin, Germany, since 2014

  • LS2 Panel Member, ERC (Consolidator 2014, 2018; Starting, 2016), 2014 – 2018

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