Prof. Dr. Silvia Arber
Biological and related sciences, Health, Neuroscience
Health
Role of TGFbeta signalling in cardiovascular development and heart repair
Role of endoglin in cardiovascular development and disease.
How endoglin modulates angiogenesis in coronary vessel development and in heart repair.
How TGFbeta signalling regulates angiogenesis.
Characterising molecular and cellular defects in Hereditary Haemorrhagic Telangiectasia to inform development of patient therapies.
English
X. Wang, S. Abraham, JAG McKenzie, N Jeffs, M Swire, V Tripathi, UFO Luhmann, CAK Lange, Z Zhai, HM Arthur, J Bainbridge, SE Moss & J Greenwood (2013) Lrg1 promotes angiogenesis by modulating endothelial TGFß signaling Nature 499(7458):306-11.
Anderberg C, Cunha S , Zhai Z , Pardali E, Cortez E, Johnson J, Franco M, Paez-Ribes M, Cordiner R, Fuxe J, Goumans MJ, Casanovas O, ten Dijke , Arthur HM, Pietras K (2013) Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination. J Exp Med. 210(3):563-79.
Mahmoud M, Allinson KR, Zhai Z, Oakenfull R, Adams RH, Ghandi P, Fruttiger M and Arthur HM. (2010) Pathogenesis of arteriovenous malformations in the absence of endoglin. Circulation Research, 106(8):1425-33.
Led my Institute's Athena Swan application- aims to support female academic career development.
Member of Heart Research UK medical review panel 2007-2013
Member of BHF project grant review panel 2011-2014
You can only see the contact information of the academics in the database if you are a registered user of AcademiaNet.
Please register here
Biological and related sciences, Health, Neuroscience
Health, Obesity, Diabetes, Immunology
Biological and related sciences, Health, Neurophysiology (synaptic physiology)
Biological and related sciences, Health, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology
Helen Arthur's research examines how genetic faults in blood vessel growth cause human diseases and how these pathways can also be harnessed to treat people who have had a heart attack.