Short CV/Education and training

  • 1963
    B.S. Chemistry, Antioch College, Yellow Springs, Ohio

  • 1967
    Ph.D. Biochemistry and Molecular Biology, Harvard Univ., Cambridge, Mass.

  • 1967 – 1969
    National Science Foundation Postdoctoral Fellow

  • 1967 – 1970
    Jane Coffin Childs Memorial Fund Fellow, Div. of Cell Biology Medical Research Council Lab. of Molecular Biology, Cambridge, England

  • 1970 – 1974
    Assistant Professor, Molecular Biophysics and Biochemistry, Yale University, New Haven, Conn.

  • 1974 – 1978
    Associate Professor, Molecular Biophysics and Biochemistry, Yale University

  • 1976 – 1977
    Josiah Macy Scholar (sabbatical), Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, and Medical Research Council Laboratory of Molecular Biology, Cambridge, England

  • 1978 – 1992
    Professor, Molecular Biophysics and Biochemistry, Yale University

  • 1984 – 1985
    Fairchild Distinguished Fellow (sabbatical), California Inst. of Technology, Pasadena, CA

  • since 1986
    Investigator, Howard Hughes Medical Institute, Yale University

  • 1991 – 2002
    Scientific Director, Jane Coffin Child Fund for Medical Research

  • 1992 – 1998
    Henry Ford II Professor of Molecular Biophysics and Biochemistry, Yale University

  • 1996 – 1999
    Chairman, Department of Molecular Biophysics and Biochemistry, Yale University

  • since 1998
    Sterling Professor of Molecular Biophysics and Biochemistry, Yale University

Selected publications

  • Steitz, J.A. (1969). Polypeptide chain initiation: Nucleotide sequences of the three ribosomal binding sites in bacteriophage R17 RNA. Nature 224, 957–964.

  • Steitz, J.A. and Jakes, K. (1975). How ribosomes select initiator regions in mRNA: Base pair formation between the 3′ terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli. Proc. Natl. Acad. Sci., USA 72, 4734–4738.

  • Lerner, M.R., Boyle, J.A., Mount, S.M., Wolin, S.L. and Steitz, J.A. (1980). Are snRNPs involved in splicing? Nature 283, 220–224.

  • Tarn, W.-Y. and Steitz, J.A. (1996). Highly diverged U4 and U6 small nuclear RNAs required for splicing of rare AT-AC introns. Science 273, 1824-1832.

  • Vasudevan, S., Tong, Y. and Steitz, J.A. (2007). Switching from repression to activation: microRNAs can upregulate translation. Science 318, 1931–1934.

  • Cazalla, D., Yario, T., and Steitz, J.A. (2010). Downregulation of a host microRNA by a Herpesvirus saimiri noncoding RNA. Science 328,1563-1566. PMCID: PMC3075239

  • Mitton-Fry, R.M., DeGregorio, S.J., Wang, J., Steitz, T.A., and Steitz, J.A. (2010). Poly(A) tail recognition by a viral RNA element through assembly of a triple helix. Science 330, 1244-1247. PMCID: PMC3074936

  • Tycowski, K.T., Shu, M.-D., Borah, S., Shi, M., and Steitz, J.A. (2012). Conservation of a triple-helix-forming RNA stability element in noncoding and genomic RNAs of diverse viruses. Cell Reports 2, 26-32. PMCID: PMC3430378

  • Brown, J.A., Valenstein, M.L., Yario, T.A., Tycowski, K.T., and Steitz, J.A. (2012). Formation of triple-helical structures by the 3′-end sequences of MALAT1 and MENβ noncoding RNAs. Proc. Natl. Acad. Sci., USA 109, 19202-19207. PMCID: PMC3511071

  • Riley, K.J., Rabinowitz, G.S, Yario, T., Luna, J., Darnell, R., and Steitz, J.A. (2012). EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency. EMBO J. 31, 2207–2221. PMCID: PMC3343464

Complete list of publications

Selected projects

  • Structure and Function of Non-coding RNA-protein Complexes from Eukaryotes, RNA Processing

Membership in scientific bodies/juries

  • CRNA, Scientific Advisory Board, University of Michigan, 2013

  • L'Oréal USA Fellowships for Women in Science Jury, 2013

  • Selection Committee for the Pearl Meister Greengard Award, 2013

  • European Research Council, Synergy Grant Evaluation, Step 2a Panel Meetings, 2012

  • Board of Scientific Counselors of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, since 2011

  • NAS Award in Molecular Biology Selection Committee, since 2009; Chair, 2011

  • Scientific Advisory Board, Institute of Biotechnology, University of Helsinki, since 2007; Chair, 2011

  • Associate Editor, Journal of Cell Biology, since 2010

  • Jane Coffin Childs Fund Board of Managers, since 2010

  • Scientific Advisory Committee, Rita Allen Foundation, since 2010

  • Gerstner Sloan-Kettering Cancer Biology Graduate Program External Advisory Committee, since 2009

  • Board Member, Rosalind E. Franklin Society, since 2009

  • Albany Medical Center Prize in Medicine and Biomedical Research National Selection Committee, since 2009

  • MIT Biology Visiting Committee, MIT, Cambridge, since 2009

  • Honorary Fellow of The New York Academy of Medicine, since 2009

  • Committee on Scientific Affairs, Rockefeller University, since 2007

  • L'Oréal UNESCO International Prize Jury, since 2007

  • Member, Institute of Medicine, since 2005

  • Honorary Member of Phi Beta Kappa, Yale Chapter, since 2005

  • Wiley Prize Jury, since 2004

  • L'Oréal Postdoctoral Fellowship Selection Committee, since 2002

  • Honorary Member, Japanese Biochemical Society, since 2002

  • Member Academia Europaea, since 2002

  • Associate Editor, RNA, since 1994

  • Member, Editorial Board, Genes and Development, since 1994

  • Fellow of the American Academy of Microbiology, since 1992

  • Member of the American Philosophical Society, since 1992

  • Associate Member, European Molecular Biology Organization, since 1987

  • Member, Connecticut Academy of Science and Engineering, since 1986

  • Member of the National Academy of Sciences, since 1983

  • Member of the American Academy of Arts and Sciences, since 1982

  • Fellow of the American Association for the Advancement of Science, since 1981

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • Married, 1 Child


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