Prof. Dr. Seema Agarwal
Physical sciences, Preparative and physical chemistry of polymersNanotechnology
Biological and related sciences, Physical sciences
Trained as an experimental physicist, Lene Oddershede works at the crossroad between physics, medicine and biology. She is an expert on optical manipulation, biophysics, interaction between light and nanoparticles, and on biophysics of cells, with a special interest in stem cells.
Biophysics, nano-bio-photonics, medical physics, stem cells, nanoparticles, nanotechnology, physics, optics
Elite Research Prize, the largest Danish public research prize, February 2015
Member of the Royal Danish Academy of Sciences and Letters, 2014
Silver medal from the Royal Danish Academy of Sciences and Letters, November 2011
CeNS Publication award, 2011
Danish Optical Society Award for Young Investigators, 2003
Danish Physical Society Award for best poster in 1994, 1995, 2003
Danish, English, German, Italian
N.S. Rossen, J.M. Tarp, J. Mathiesen, M.H. Jensen, L.B. Oddershede. Long-range ordered vorticity patterns patterns in living tissue induced by cell division. Nature Communications, vol. 5 p. 5720 (1-7) (2014).
K. Norregaard, M. Andersson, P.E. Nielsen, S. Brown, L.B. Oddershede. Tethered particle analysis of supercoiled circular DNA using PNA handles. Nature Protocols, vol. 9 p. 2206 (2014).
H. Ma, P. Tian, J. Pello, P.M. Bendix, L.B. Oddershede. Heat generation by irradiated complex composite nanostructures. Nano Letters, vol. 14 p.612-619 (2014).
K. Norregaard, M. Andersson, K. Sneppen, P.E. Nielsen, S. Brown, L.B. Oddershede. DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch. PNAS, vol. 110 p.17386-17391 (2013).This paper prompted an invitation for an Addendum in Bacteriophage 2014.
T. Jakociunas, M.D. Jordo, M.A. Mebarek, C.M. Bunner, J. Verhain-Hansen, L.B. Oddershede, G. Thon, Subnuclear relocalization and silencing of a chromosomal region by an ectopic rDNA repeat, PNAS, vol. 110 p.E4465-E4473 (2013).
Rated as 'of outstanding interest' in Curr Opinion in Cell Bio. vol. 28 p. 54 (2014).
H. Ma, P.M. Bendix, L.B. Oddershede. Large-Scale Orientation Dependent Heating from a Single Irradiated Gold Nanorod. Nano Letters vol.12 p.3954-3960 (2012).
L.B. Oddershede. Force probing of individual molecules inside the living cell is now a reality. Nature Chemical Biology, vol 8 p.879-886 (2012).
P. Gross, N. Laurens, L.B. Oddershede, U. Bockelmann, E.J.G. Peterman, G.J.L. Wuite. Quantifying how DNA stretches, melts and changes twist under tension, Nature Physics vol. 7 p.731-736 (2011).
A. Kyrsting, P.M. Bendix, D.G. Stamou, and L.B. Oddershede. Heat Profiling of Three-Dimensionally Optically Trapped Gold Nanoparticles using Vesicle Cargo Release. Nano Letters, vol 11 p.888-892 (2011).
J.H. Jeon, V. Tejedor, S. Burov, E. Barkai, C. Selhuber, K. Berg-Sørensen, L. Oddershede, R. Metzler. In vivo anomalous diffusion and weak ergodicity breaking of lipid granules. Physical Review Letters, vol. 106 p.048103 (2011). This paper received the CeNS award for an outstanding publication.
Stem cell decision making
Development of a plasmon based cancer therapy
Force mapping during cancer cell division and migration
Member of the Royal Danish Academy of Sciences and Letters, since 2014
Danish member of ERC COST action no 1205 (optics and microfluidics), 2012 – 2016
Danish National Committee for Biophysics, since 2007
NBI Visionary and Strategic Committee, 2003 and 2008 – 2013
Board of BIOP graduate school, 2003 – 2005
NBI educational committee, 2003 – 2010
Board of high-technological network for biophotonics, 2005 – 2006
Committee of Future Education in Natural Sciences, 2002 – 2003
LBO is expert on in vivo manipulation of living matter from the single molecule to whole cell level, on optical manipulation of individual metallic nanoparticles, on matter-light-nanoparticle interactions, and on in vitro investigations of nucleic acids. Methodologically, areas of expertise include optical manipulation, force spectroscopy, fluorescent visualization (also super-resolution), and single particle tracking.
Lene B. Oddershede was born in 1970.
She is married to Ulrich J. Quaade and they have 3 sons born 1997, 2000 and 2006.
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Physical sciences, Preparative and physical chemistry of polymersNanotechnology
Physical sciences, Quantum simulation, Ultracold atoms
Biological and related sciences, Physical sciences, Environmental virology, Molecular and structural biology, biochemistry
Physical sciences, Asteroseismology