Short CV/Education and training

  • 1992
    BSc in Biochemistry and Genetics

  • 1993
    MSc in Environmental Sciences

Selected publications

  • Mellough CB, Collin J, Khazim M, White K, Sernagor E, Steel D and Lako M (2015) IGF-1 signalling plays an important role in the formation of three dimensional laminated neural retina and other ocular structures from human embryonic stem cells. Stem Cells 33:2416-30 (Cover page image).

  • Tilgner K, Neganova I, Yung S, Al-Aama J, Singhapol C, Saretzki G, Evans J, Gorbunova V, Gennery A, Przyborski S, Stojkovic M, Armstrong L, Jeggo P and Lako M (2013) A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors. Cell Death and Differentiation 20:1089-100.

  • Yung S, Ledran M, Moreno-Gimeno I, Conesa A, Montaner D, Dopazo J, Dimmick I, Slater NJ, Marenah L, Real PJ, Paraskevopoulou I, Bisbal V, Burks D, Santibanez-Koref M, Moreno R, Mountford J, Menendez P, Armstrong L, Lako M. (2011) Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells. Hum Mol Genet. 20(24):4932-46

  • Zhang X, Neganova I, Pryzborski S, Yang C, Cooke M, Atkinson SP, Anyfantis G, Fenyk S, Keith WN, Hoare SF, Hughes O, Strachan T, Stojkovic M, Hinds PW, Armstrong L and Lako M. (2009) A role for NANOG in G1 to S transition in human embryonic stem cell through direct binding of CDK6 and CDC25A. J. Cell Biol. 184:67-82.

  • Ledran MH, Krassowska A, Armstrong L, Dimmick I, Renstrom J, Lang R, Yung S, Santibanez-Coref M, Dzierzak E, Stojkovic M, Oosterndorp RAJ, Forrester L and Lako M (2008) Efficient haematopoietic differentiation of human embryonic stem cell on stromal cells derived from hematopoietic niches. Cell Stem Cell 3:85-98.

Complete list of publications

Selected projects

  • Exploiting the power of human induced pluripotent stem cells to generate synthetic retina in vitro for cell based therapies, drug discovery and disease modelling

  • Improving our understanding of autosomal dominant retinitis pigmentosa using PRPF31 patient specific iPSC

  • Assessing the feasibility of iPSC to provide a disease model for age related macular degeneration

  • Stem cells for biological assays of novel drugs and predictive toxicology

  • Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cell as a tool to optimise photoreceptor transplantation

Membership in scientific bodies/juries

Editorial Board

  • Associate Editor for Regenerative Medicine (January 2005 to December 2007)

  • Associate Editor for Stem Cells (February 2008 to date)

  • Member of the editorial board for PlosOne (September 2011 to date)

  • Member of the editorial board for Scientific Reports (March 2011 to date)

Panel Member

  • Independent Invited Expert to Wellcome Trust Project Review Group (2015)

  • Chair of the fundamental biology panel for the French ANR LABEX midway scientific review, France (June 2015)

  • Co-chair of Connecticut Stem Cell Review Scientific Panel (January 2012 to 2014)

  • Member of the Swedish Science Council panel Treatments of the Future (October 2012)

  • Member of the Health Panel of Finish Academy (January 2013)

  • Member of the Connecticut Stem Cell Review Scientific Panel (January 2007 to 2014)

  • Member of the CGD Scientific Panel (January 2005 to December 2012)

  • Member of the French National Research Agency grant review panel (January 2009 to date)

  • Member of the French ANR LABEX scientific panel (January 2012 – to date)

  • Inserm institute reviewer (January 2007- to date)

Soft Skills/Other activities and achievements

Other activities and achievements/family

  • piano playing , learning foreign languages, spending time with my two children, riding a bike and cooking exotic food


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