Short CV/Education and training

EDUCATION

  • 1977
    MD degree, University of Ferrara, Italy

  • 1980
    Specialization in Experimental Oncology, University of Ferrara, Italy

  • 1985
    PhD in Tumor Immunology, Karolinska Institute, Stockholm, Sweden

  • 1988
    Lecturer (Docent) of Tumor Biology with specialization in Tumor Immunology

APPOINTMENTS

  • 1978 – 1992
    Research associate at the Department of Tumor Biology, Karolinska Institutet

  • 1986
    Visiting Scientist, Netherland Cancer Institute, Amsterdam, The Netherlands

  • 1991 – 1992
    Visiting Scientist, Department of Cancer Studies, University of Birmingham, UK

  • 1992 – 1997
    Research fellow of the Swedish Cancer Society

  • 1995
    Visiting Scientist, Department of Cell Biology, MIT, Boston, MA

  • 1996
    Professor of Tumor Biology, University of Lund, Lund, Sweden

  • since 1997
    Professor of Virology, Karolinska Institutet, Stockholm, Sweden

  • 2002 – 2003
    Visiting Professor Department of Cell Biology, Harvard Medical School, Boston, MA

Selected publications

  • de Campos-Lima, P.-O., R. Gavioli, Q.-J. Zhang, L. Wallace, M. Rowe, A. B. Rickinson and M. G. Masucci (1993). "HLA-A11 epitope loss isolates of Epstein-Barr virus from a highly A11+ population." Science 260: 98-100.

  • Levitskaya, J., m. Coram, V. Levitsky, S. Imreh, P. M. Stegerwald-Mullen, G. Klein, M. G. Kurilla and M. G. Masucci (1995). "Inhibition of antigen processing by the internal repeat region of the Epstein-Barr Virus nuclear antigen-1." Nature (Lond.) 375: 685-688.

  • Sharipo, A., M. Imreh, A. Leonchiks, S. Imreh and M. G. Masucci (1998). "A minimal glycine-alanine repeat prevents the interaction of ubiquitinated I kappaB alpha with the proteasome: a new mechanism for selective inhibition of proteolysis." Nature Med. 4(8): 939-944.

  • Dantuma, N., K. Lindsten, R. Glas, M. Jellne and M. G. Masucci (2000). "Short-lived green fluorescent proteins for quantification of ubquitin/proteasome-dependent proteolysis in living cells." Nature Biotech. 18: 538-543.

  • Gavioli, R., Frisan, T., Vertuani, S., Bornkamm, G.W., and Masucci, M.G. (2001). C-myc overexpression activates alternative pathways for maintenance of intracellular proteolysis in lymphoma cells. Nature Cell Biol. 3, 283-288

  • Gruhne B, Sompallae R, Marescotti D, Kamranvar SA, Gastaldello S, Masucci MG. 2009 The Epstein-Barr virus nuclear antigen-1 promotes genomic instability via induction of reactive oxygen species. Proc Natl Acad Sci U S A. 106:2313-2318

  • Gastaldello S, Hildebrand S, Faridani O, Callegari S, Palmkvist M, Di Guglielmo C, Masucci MG. 2010. A deneddylase encoded by Epstein Barr virus promotes viral DNA replication by regulating the activity of cullin-RING-ligases. Nature Cell Biol. 12:351-361

  • Gastaldello S, Chen X, Callegari S, Masucci MG. 2013. Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells. PLoSPathogens 9(10):e1003664.

  • Kamranvar S., Chen X. Masucci MG. 2013. Telomere dysfunction and activation of Alternative Lengthening of Telomeres in B-lymphocytes infected by Epstein-Barr virus. Oncogene. 5;32(49):5522-5530


Membership in scientific bodies/juries

  • EBMO

  • Swedish Academy of Science

  • Nobel Assembly for Physiology and Medicine

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