Short CV/Education and training


  • 1987 – 1992
    Diploma in Biology; University of Tartu, Estonia

  • 1993 – 1995
    PhD student; University of Helsinki, Finland

  • 1996 – 1998
    Postdoctoral fellow; Institute of General Biology, Ludwig-Maximilians-Universität München, Germany

  • 1999 – 2000
    Researcher; Josephine Bay Paul Center in Comparative Molecular Biology and Evolution, Marine Biological Laboratories, Woods Hole, USA

Past positions

  • 2002 – 2003
    senior researcher; University of Tartu, Estonia

  • 2004 – 2009
    research professor; University of Tartu, Estonia

  • 2009 – 2016
    full professorship in Human Molecular Genetics, Faculty of Science and Technology, University of Tartu, Estonia

Current position

  • Since 2016
    full professorship in Human Genetics, Faculty of Medicine, University of Tartu, Estonia

Selected publications

  • 1. Kasak L, Punab M, Nagirnaja L, Grigorova M, Minajeva A, Lopes AM, Punab AM, Aston KI, Carvalho F, Laasik E, Smith LB; GEMINI Consortium, Conrad DF, Laan M (2018) Bi-allelic Recessive Loss-of-Function Variants in FANCM Cause Non-obstructive Azoospermia. Am J Hum Genet 103(2):200-212.

  • 2. Rull K, Grigorova M, Ehrenberg A, Vaas P, Sekavin A, Nõmmemees D, Adler M, Hanson E, Juhanson P, Laan M (2018) FSHB −211 G>T is a major genetic modulator of reproductive physiology and health in childbearing age women. Hum Reprod 33(5):954-966.

  • 3. Grigorova M, Punab  M, Poolamets  O, Adler  M, Vihljajev V, Laan M (2017) Genetics of Sex Hormone-Binding Globulin and Testosterone Levels in Fertile and Infertile Men of Reproductive Age. Journal of the Endocrine Society, 1(6) 560–576.

  • 4. Kasak L, Rull K, Sõber S, Laan M (2017) Copy number variation profile in the placental and parental genomes of recurrent pregnancy loss families. Sci Rep 7:45327.

  • 5. Punab M, Poolamets O, Paju P, Vihljajev V, Pomm K, Ladva R, Korrovits P, Laan M (2017) Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts. Hum Reprod 32(1):18-31.

  • 6. Sõber S, Rull K, Reiman M, Ilisson P, Mattila P, Laan M (2016) RNA sequencing of chorionic villi from recurrent pregnancy loss patients reveals impaired function of basic nuclear and cellular machinery. Sci Rep 6:38439.

  • 7. Juhanson P, Rull K, Kikas T, Laivuori H, Vaas P, Kajantie E, Heinonen S, Laan M (2016) Stanniocalcin-1 Hormone in Nonpreeclamptic and Preeclamptic Pregnancy: Clinical, Life-Style, and Genetic Modulators. J Clin Endocrinol Metab 101(12):4799-4807.

  • 8. Sõber S, Reiman M, KikasT, Rull K, Inno R, Vaas, P, Teesalu P, Lopez Marti JM, Mattila P, Laan M (2015) Extensive shift in placental transcriptome profile in preeclampsia and placental origin of adverse pregnancy outcomes. Sci Rep 5:13336.

  • 9. Kasak L, Rull K, Vaas P, Teesalu P, Laan M (2015) Extensive load of somatic CNVs in the human placenta. Sci Rep 5:8342.

  • 10. Putku M, Kals M, Inno R, Kasela S, Org E, Kožich V, Milani L, Laan M (2015) CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs. Hum Genet 134(3):291-303.

Complete list of publications

Selected projects

  • Project “Development of novel non-invasive biomarkers for fertility and healthy pregnancy” (HAPPY PREGNANCY)

Membership in scientific bodies/juries

  • Professional Societies:

    Estonian Society of Human Genetics

    European Society of Human Genetics

    European Society of Endocrinology

    The European Academy of Andrology

  • Assiciate Editor:

    Human Reproduction

    Scientific Reports

  • Expert and reviewer for Estonian Research Council, and for a number of national, private and EC level grant agencies in Europe.

  • Member of scientific programme committee:

    European Congress in Endocrinology 2015

    10th European Congress of Andrology 2018

    European Human Genetics Conference 2018-2022

Soft Skills/Other activities and achievements

Soft Skills

  • I have long-term experience in teaching human genetics and genomics to the undergraduate and graduate students in biomedicine, gene technology, biology, pharmacy, medicial and dental schools; as well as lecturing about advances in genetics to non-specialist academic and non-academic audience.

Other activities and achievements/family

  • Married; mother of two daughers and two sons.


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