Prof. Nica Borgese

Education and training

• 1964
  "Maturità classica" (diploma oriented in the humanistic disciplines) from the public lyceum "Michelangiolo", Florence, Italy.
  
  

• 1964 – 1966
  Undergraduate, Faculty of Science, University of Paris. Basic courses in Chemistry, Physics and Biology
  
  

• 1966 – 1972
  Graduate student, the Rockefeller University, New York
  
  

• 1968 – 1972
  Thesis research in the laboratory of David Sabatini. The research for my thesis in Cell Biology concerned the interaction between ribosomes and membranes of the Endoplasmic Reticulum, and led to the demonstration of a proteinaceous receptor for ribosomes on the rough ER membrane
  
  

• 1972
  Ph.D., The Rockefeller University, New York
  
  

• 1973 – 1977
  Postdoctoral training in Cell Biology with Prof. Jacopo Meldolesi, C.N.R. Center for Cytopharmacology, Milano. The research concerned the biogenetic relationship between membranes of the secretory pathway.
  
  

Academic Record

• 1974 – 1988
  Investigator of the Italian National Research Council (C.N.R) – C.N.R. Center for Cytopharmacology, Milano
  
  

• since 1980
  Group Leader, C.N.R. Institute of Neuroscience, Milano
  
  

• 1984
  Short term E.M.B.O. fellowship for collaboration with Dr. Kathryn Howell, E.M.B.L., Heidelberg
  
  

• 1985
  Visiting Scholar, on a long-term EMBO fellowship, at the Department of Anatomy and Cellular Biology, Harvard Medical School (Laboratory of Joan Ruderman)
  
  

• 1988 – 1994
  Associate Professor in General Biology, Faculty of Pharmacy, University of Milano
  
  

• 1994 – 2014
  Professor of Biology, Faculty of Pharmacy, University of Catanzaro “Magna Graecia”
  
  

• 2003 – 2011
  Director, Department of Pharmacobiological Science, University of Catanzaro “Magna Graecia”
  
  

Current Position

• Group Leader, CNR Institute of Neuroscience, Milano

• Fossati M., Colombo S., Borgese N. (2014) A positive signal prevents secretory membrane cargo from recycling between the Golgi and the ER. Embo J., 33: 2080-97, doi: 10.15252/embj.201488367

• Giordano F., Saheki Y., Idevall-Hagren Y., Colombo S.F.., Pirruccello M., Milosevic I., Gracheva E.O., Bagriantsev S.N., Borgese N., De Camilli P. (2013) PI(4,5)P2 dependent and Ca2+-regulated ER-Plasma Membrane Interactions mediated by the Extended-Synaptotagmins. Cell 153: 1494-1509

• Maiuolo J., Bulotta S., Verderio C., Benfante R., Borgese N. (2011) Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein. Proc Natl Acad Sci U S A. 108:7832-7837.

• Ronchi P., Colombo S., Francolini M., Borgese N. (2008) Transmembrane Domain-Dependent Partitioning of Membrane Proteins within the Endoplasmic Reticulum. J. Cell Biol. 181: 105-118.

• Brambillasca S., Yabal M., Makarow M., Borgese N. (2006) Unassisted translocation of large polar domains across phospholipid bilayers. J. Cell Biol 175:767-777.

• Mechanism of targeting of tail-anchored membrane proteins

• Mechanism of spontaneous insertion of tail-anchored membrane proteins

• Mechanisms of Endoplasmic Reticulum plasticity

• The role of the Endoplasmic Reticulum adaptor protein, VAP-B, in motorneuronal physiology

• Review Panel for the ERC, starting grants, LS3; 2013-2013

• Review Panel of the Research Council for Biosciences and Environment (RCBE) and Research Council for Health (RCH) of the Academy of Finland; 2009

• Scientific Committee of Telethon Foundation; 2009-2012

• Member of the International Affairs Committee, American Society for Cell Biology; 1998-2000

• Member of the Directive Council of the Italian Society for Cell Biology and Differentiation (ABCD); 1987-90

• Member of the Editorial Board of "Subcellular Biochemistry"; 1986-2002

Additional interests

• Hiking, skiing, music

Other activities and achievements/family

• Married, one daughter

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