Short CV/Education and training

  • Since 2021
    ERC group leader & INSERM Research Director, INMG (NeuroMyoGène institute)/ INSERM-CNRS-Univ/ Lyon University, France

  • 2017 – 2020
    Senior group leader & INSERM Research Director (full professor in 2019), INM (Institut des Neurosciences de Montpellier)/ INSERM/ Montpellier University, France

  • 2012 – 2017
    ATIP-Avenir group leader & INSERM CR1 (associate professor in 2011), INM (Institut des Neurosciences de Montpellier)/ INSERM/ Montpellier University, France

  • 2007 – 2011
    INSERM researcher CR2 (assistant professor in 2007) in Dr A. Represa’s lab, INMED (Institut de Neurobiologie de la Méditerranée)/ INSERM/ Aix-Marseille University, France

  • 2003 – 2007
    Postdoctoral researcher in Pr D.W. Cleveland’s lab, LICR (Ludwig Institute for Cancer Research), Neurobiology & Cell biology department/ University of California, San Diego, USA

  • 1998 – 2002
    PhD student in Pr JL Mandel’s lab (PI: Koenig), IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), Human Genetic department/ Louis Pasteur University, Strasbourg, France

Education

  • 2010
    Diploma to supervise PhD students & research (H.D.R); Aix-Marseille II University, France

  • 2002
    Ph.D in Human Genetics/ IGBMC / Louis Pasteur University, Strasbourg, France

  • 1998
    Master II / Claude Bernard University, Lyon, France

Selected publications

  • The dazzling rise of neurofilaments: Physiological functions and roles as biomarkers. Bomont P. Curr Opin Cell Biol. (2021) Jan 13:S0955-0674(20)30146-0.

  • E3 Ubiquitin Ligases in Neurological Diseases: Focus on Gigaxonin and Autophagy. Lescouzères L, Bomont P. Front Physiol (2020) 11:1022.

  • Neurofilaments: neurobiological foundations for biomarker applications. Gafson AR, Barthélemy NR, Bomont P et al. Brain (2020) 143(7):1975-1998.

  • Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy. Arribat Y*, Mysiak KS*, Lescouzères L, Boizot A, Ruiz M, Rossel M, Bomont P. J Clin Invest. (2019) 129(12):5312-5326.

  • Gigaxonin E3 ligase governs ATG16L1 turn over to control autophagosome production. Scrivo A, Codogno P, Bomont P. Nat Commun. (2019) 10(1):780.

  • Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy. Colin E*, Daniel J*, Ziegler A* (…), Bomont P*, Liebau E*, Bonneau D*. Am J Hum Genet. (2016) 99(3):695-703. (Co-last & co-first authors)

  • Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies. Angebault C*, Guichet PO*, Talmat-Amar Y*, (…), Rozet JM, Bomont P, Hamel CP, Lenaers G. Am J Hum Genet. (2015) 97(5):754-60. (Co-first author)

  • Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. J Clin Invest. (2013) 123(5):1964-75.

  • Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway. Cleveland DW, Yamanaka K, Bomont P. Hum Mol Genet. (2009) Apr 15;18(8):1384-94.

  • Unstable microtubule capture at kinetochores depleted of the centromere protein CENP-F. Bomont P, Maddox P, Shah JV, Desai AB, Cleveland DW. EMBO J. (2005) 24(22):3927-39.


Selected projects

  • ERC-CoG: "Neurofilaments in health and neurodegenerative diseases", 2021 – 2026

  • AFM-Téléthon, strategic project: "Therapies for Giant Axonal Neuropathy", 2021 – 2024

Membership in scientific bodies/juries

  • Candidate for the scientific board, French Cell Biology Society “SBCF”, since 2021 (pending)

  • Member of the international Zebrafish society "IZFS", since 2021

  • Member of the international Peripheral Nerve Society “PNS”, since 2020

  • Nomination at the scientific board, World Intermediate Filaments Society, since 2019

  • Elected Board Member, “CFATG-autophagy” society, since 2018

  • Member of the European COST action on Autophagy « Transautophagy » (CA15138), since 2018

  • Board member of the Neuroscience association of Montpellier “Comédie des Neurones”, since 2015

  • Member of the European COST action « EuroCellNet » (CA15214), since 2015

  • Member of the European zebrafish society, since 2015

  • Member of the French Autophagy society “CFATG”, since 2015

  • Member of the French Neuroscience society, since 2014

  • Member of the French Cell Biology Society “SBCF”, since 2014

  • Member & WGL of the European COST action « Proteostasis» (BM1307), 2013 – 2018

Media coverage

  • Written press: 20 minutes

  • Television: France 3 (TV shows & TV news)

  • YouTube: videos

  • Twitter: patient's associations, regional and national agencies

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