Short CV/Education and training

  • Katrien De Bock was born in Belgium in 1980 and is a Belgian citizen. She received her Master in Rehabilitation sciences in 2002.

  • During her PhD-period at the Research Center for Exercise and Health (University of Leuven – Belgium – Oct 2002 to Sept 2007), she focused her research on exercise physiology and studied metabolic plasticity in muscle during exercise in the fasted state. From Oct 2007 to June 2013, she conducted a postdoctoral training at the Vesalius Research Center, Flemish Interuniversity Institute of Biotechnology (VIB – University of Leuven) under the mentorship of Prof. Peter Carmeliet. Here, she studied the link between angiogenesis and metabolism during development and disease.

  • In Sept 2014, Katrien De Bock received an assistant professorship position at University of Leuven (Belgium), but soon thereafter moved to Madrid (Spain) for an intensive research stay in the laboratory of Prof. Julian Aragonés where she studied the link between hypoxia and metabolism (02-08/ 2014).

  • In October 2015, she decided to take up a professorship at ETH in Zürich where she is currently leading the laboratory of exercise and health.

Selected publications

  • Veys K, Fan Z, Ghobrial M, Bouche A, Garcia-Caballero M, Vriens K, Conchinha NV, Seuwen A, Schlegel F, Gorski T, Crabbe M, Gilardoni P, Ardicoglu R, Schaffenrath J, Casteels C, De Smet G, Smolders I, Van Laere K, Abel ED, Fendt SM, Schroeter A, Kalucka J, Cantelmo AR, Walchli T, Keller A, Carmeliet P, De Bock K. Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity. Circ Res. 2020. PubMed PMID: 32404031.

  • D'Hulst G, Soro-Arnaiz I, Masschelein E, Veys K, Fitzgerald G, Smeuninx B, Kim S, Deldicque L, Blaauw B, Carmeliet P, Breen L, Koivunen P, Zhao SM, De Bock K. PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase. Nat Commun. 2020;11(1):174. PubMed PMID: 31924757.

  • Zhang J, Muri J, Fitzgerald G, Gorski T, Gianni-Barrera R, Masschelein E, D'Hulst G, Gilardoni P, Turiel G, Fan Z, Wang T, Planque M, Carmeliet P, Pellerin L, Wolfrum C, Fendt SM, Banfi A, Stockmann C, Soro-Arnaiz I, Kopf M, De Bock K. Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization. Cell Metab. 2020;31(6):1136-53 e7. PubMed PMID: 32492393.

  • Gorski TDB, K. Metabolic Interactions Between the Endothelium and the Muscle Microenvironment. Vasc Biol. 2019;1(1):H1-H8. PubMed PMID: WOS:000463529300051.

  • Schoors S, De Bock K, Cantelmo AR, Georgiadou M, Ghesquiere B, Cauwenberghs S, Kuchnio A, Wong BW, Quaegebeur A, Goveia J, Bifari F, Wang X, Blanco R, Tembuyser B, Cornelissen I, Bouche A, Vinckier S, Diaz-Moralli S, Gerhardt H, Telang S, Cascante M, Chesney J, Dewerchin M, Carmeliet P. Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis. Cell Metab. 2014;19(1):37-48. PubMed PMID: 24332967.

  • De Bock K, Georgiadou M, Schoors S, Kuchnio A, Wong BW, Cantelmo AR, Quaegebeur A, Ghesquiere B, Cauwenberghs S, Eelen G, Phng LK, Betz I, Tembuyser B, Brepoels K, Welti J, Geudens I, Segura I, Cruys B, Bifari F, Decimo I, Blanco R, Wyns S, Vangindertael J, Rocha S, Collins RT, Munck S, Daelemans D, Imamura H, Devlieger R, Rider M, Van Veldhoven PP, Schuit F, Bartrons R, Hofkens J, Fraisl P, Telang S, Deberardinis RJ, Schoonjans L, Vinckier S, Chesney J, Gerhardt H, Dewerchin M, Carmeliet P. Role of PFKFB3-driven glycolysis in vessel sprouting. Cell. 2013;154(3):651-63. PubMed PMID: 23911327.

  • De Bock K, Georgiadou M, Carmeliet P. Role of endothelial cell metabolism in vessel sprouting. Cell Metab. 2013;18(5):634-47. PubMed PMID: 23973331.



Complete list of publications

Selected projects

  • Understanding Exercise-Induced Endothelial Metabolic Reprogramming To Promote Ischemic Revascularization (Swiss National Science Foundation – SNSF)

  • UNDERSTANDING THE METABOLIC CROSSTALK BETWEEN THE MUSCLE AND THE ENDOTHELIUM: IMPLICATIONS FOR EXERCISE TRAINING AND INSULIN RESISTANCE (European Research Council – ERC Starting Grant)

Media coverage

  • www.musec.ethz.ch

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