The growth of neuronal and vascular networks is controlled by the same molecules. Now Amparo Acker-Palmer plans to study the communication between neurons and blood vessels in the brain. She hopes to use her findings to gain important insights into dementia progression, and into other mental illnesses.
Healthy cells reduce their growth when there is a lack of oxygen, or hypoxia. But hypoxia is a characteristic of malignant tumours. The team of Prof. Amparo Acker-Palmer from Goethe University Frankfurt and colleagues from the University of Giessen could show how cancer cells succeed at circumventing the genetic program of growth inhibition.