Plant Ecology, Conservation Biology, Landscape Genomics

The focus of my research is on examining the impact of habitat fragmentation on gene- to species-level aspects of biodiversity and related ecosystem services.

Evolutionary biology, Evolutionary genetics

Sex differences, Sex chromosome evolution, Sexual selection

Environmental virology, Molecular and structural biology, biochemistry

Giant viruses diversity, Giant viruses physiology, Host/pathogen cross-talk, Role of DNA viruses in evolution, viruses and the origin of life

Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Tumour Biology

Neurovascular link, Neurodevelopment, Developmental and pathological angiogenesis, Glioma invasion

Cell Biology, Cellular signaling, Cancer biology, Cancer therapy

Molecular mechanisms of cancer cell resistance to therapy, autophagy, cell death pathways, endoplasmic reticulum stress, immunogenic cell death, oxidative stress

Evolutionary biology, Animal behaviour, Gender studies, Science studies

Feminist science studies History of evolutionary biology Gender/queer perspectives on biology Anti-oppressive biology teaching

cell biology, molecular biology, biomedicine

cell death, lysosomes, apoptosis, autophagy, cancer biology, neurobiology, high-content screening

Cell Biology, Molecular Biology, Biochemistry, Microscopy

Cell organization and dynamics cytoskeleton cellular transport cell differentiation migration and division tissue morphogenesis

Evolution, genomics, bioinformatics

I am interested in understanding the evolutionary mechanisms that are behind the emergence of novel genes in genomes. I am also studying the role of repetitive sequences in the expansion of coding sequences and the formation of novel protein domains.

Molecular biology, molecular microbiology, biochemistry, membrane protein biochemistry

Bioelectrochemistry, Synthetic Biology, Chemical Biology

Engineering of Electron Transfer Pathways Genetic Code Expansion

Translational research, invasion, metastasis, disseminated tumor cells, transcription, tumor-associated proteolysis, targeted therapy, micro-RNAs, molecular staging of cancer

Natural Resources

Ecology, Behavioural Ecology, Chemical Ecology, Evolutionary Ecology

Neurophysiology (synaptic physiology)

Epilepsy (development)

Molecular Evolution, Cell and Molecular Biology

host-adapted bacterial genomes, interplay between bacteria and higher organisms

Biochemistry and biophysics

Structural biology (protein X-ray crystallography) Membrane proteins Metalloproteins Proteoliposomes Planar lipid membranes Electrophysiology Spectroscopy

Internal medicine, Hematology - hemostasis, Clinical laboratory sciences - hematology

Pathophysiology of hemostasis and thrombosis Clinical research in the field of hemostasis and thrombosis

Bioinformatics, computational genomics and modeling molecular evolution

Together with my students I work on theoretical aspects of modeling molecular evolution as well as data-driven applications of our new methodologies. We are broadly interested in applying computational methods to study the process of gene and genome evolution and in particular the process of adaptive genetic change. Growing genome-scale sequences and information from complimentary disciplines of transcriptomics, proteomics and metabolomics have begun to seriously impact genomics. But the challenge of understanding the dynamics of such large-system data can only be met through an integration of organism, molecular, and mathematical disciplines. New techniques need to be developed for discovering complex patterns from multi-faced systems biology data.

Molecular Microbiology, Microbial Proteomics and Redox biology

1) Bacterial redox-sensing regulators and the role of bacterial redox buffer 2) Proteomics and Thiol-Redox proteomics in Gram-positive bacteria 3) Bacterial secretome analyses

Neuroscience

Neuronal circuits, motor behavior, genetics

Evolutionary ecology

Insect immunity Host-pathogen interactions Ecological immunology

Molecular biotechnology, biochemistry, synthetic biology

Biochemistry Molecular biology Protein engineering Protein design Synthetic biology Systems biology Tumour biology

Biogeochemical cycles, vegetation modelling, climate change

Interactions between climate change - changes in land use - terrestrial ecosystems Interactions between fire–climate–vegetation

Biochemistry, Molecular and Cell Biology

Mitochondrial Pathophysiology Intracellular Signaling Intercellular Communication Neuroenergetics Neurodegeneration Hypoxia/Ischemia Neuroprotection

Membranes and Transport

Cellular Metabolism, Membranes and Transport, Molecular Medicine

Developmental Biology

Cell fate specification Cell signalling Gene expression

Plant Sciences

Plant nutrition/ Adaptation to abiotic stress - excess and deficiency of micronutrients-metals/ Regulation/ Transport

Molecular and cellular neurobiology

Cortical development Cortical injury

Molecular Evolution, Evolution of antibiotic resistance

I'm interested in the ancient evolutionary origins of core cellular processes. My work is also concerned with how bacteria have adapted components of these core processes in their evolution of antibiotic resistance.

Molecular Biology and Cell Biology and Biochemistry and Biology

DNA topoisomerases Leukaemia

Molecular Medicine, Genetics, Epigenetics, Hearing and deafness

Hereditary hearing loss, Epigenomics of the auditory system

Meiosis, chromatin structure regulation, spermatogenesis, fertility

Chromosome pairing, chromatin reorganisation during gametogenesis, the impact of the paternal epigenome on early embryo development

Molecular Biology

Cell Signaling

Medical genetics, Pediatric genetic diseases, developmental biology

Ciliopathies, primary cilium biology, genetic and phenotypic variability in Mendelian disorders

Molecular Medicine

Molecular Medicine, RNA, Neuroscience

Genomic, Computational Biology

Structural Biology and Biophysics, Genomic and Computational Biology, Systems Biology

Functional dissection of signal transduction pathways in lymphocyte activation and apoptosis and dysregulation of these processes un lymphoproliferative, immunodeficiency and pathogen-related diseases

Immunology, Molecular Medicine, Signal Transduction

Biological Inorganic Chemistry, Magnetic Resonance spectroscopies, NMR, Structural Biology

Proteins and Biochemistry, Structural Biology and Biophysis, Systems Biology, Metals in Life Sciences, Cellular Structural Biology, Structural Vaccinology

Science and Technology of Materials, Bioorganic chemistry

Bio-nano-medicine, Drug delivery systems

Stem cell biology, genome instability, development, aging

Stem cell regulation, genome maintenance, stem cell aging, stem cell epigenetics, somatic mutation

Structural Biology, Telomere Structure, Chromatin Structure

My areas of research are telomere structure, dynamics and telomerase recruitment and chromatin structure and regulation.

Microbiology, Virology, Pathogens

Retrovirology, Immuno-virology, Pathogenesis, HIV/AIDS Basic research at the interface of clinical research (translational research) Mechanisms of protection against HIV/SIV infections and/or AIDS

Plant molecular biology

Gene regulation under abiotic stress Chromatin and transcription Signal transmission Proteomics Plant hormones (ABA)

Developmental biology, molecular biology

regeneration and development of tissue and organs biology of stem cells

Biochemistry (protein biochemistry)

Protein crystallography Regulatory mechanisms of visual signal transduction Viral proteases Protein–ligand interactions with SH3 proteins Motor proteins Protein aggregation Protein folding

Evolutionary biodemography

Development of new concepts, models, and theories for understanding the evolution of aging in light of biodiversity

Pflanzengenetik, Pflanzenentwicklungsbiologie, Stressbiologie, Epigenetik

Interaktion Pflanzenentwicklung-Umwelt, Stressgedächtnis

Plant Biology

Intercellular communication / Plasmodesmata / Membrane contact site / Membrane lipid

G protein-coupled receptors, proteins, peptide pharmaceutical drugs, biocompatible material

Peptide hormones/GPCR Chemical modification of proteins Tumour research/oncology Metabolism research Biomaterials/surface modification

Protein biochemistry, malaria, structural biology, drug development

Biochemistry of redox metabolism Rational development of drugs to fight malaria and tumour-based diseases Parasite-host interactions Redox proteins Selenoproteins

Microbiology, synthetic biology, molecular genetics, microbial genomics

Symbiotic and pathogenic microbe plant interactions Bacterial regulatory networks

Cell biology, biochemistry

Genome stability, chromatin biology, ubiquitin, protein homeostasis, posttranslational modifications, mass spectrometry-based proteomics

Microbiology

Microbiology Cell biology Microbial development Microbial cell-cell communication

Biotechnology, microbiology, biological plant protection

Microbial diversity Environmental biotechnology

Biochemistry, molecular biology, structural biology, biophysics

Gene expression Protein synthesis Ribosomes Translational control Protein targeting and translocation of membrane proteins Cryo-electron microscopy

Immunology, Developmental Biology, Molecular Biology

Epigenetics Stem cells and cell fate decisions Monoallelic expression Cancer Regulation of immune cell development

Yeast Genetics, Genomics and Cell Biology; Candida albicans Genome dynamics; Drug Resistance in pathogenic fungi; Rapid evolutionary processes; Centromeres, Replication, Telomeres, Repetitive DNA, Aneuploidy

Pharmacology, bio-engineering, imaging, biotechnology, Biology, Neurosciences, Cell Biology, Cellular and Molecular Neuroscience, Vascular Biology, Neurobiology

Brain ischemia, stroke, brain tumour, hypoxia, hypoxia-inducible factors, regeneration, neuroprotection, cell therapy, mesenchymal stem cell, imaging, therapeutic

Signal Transduction

Chromatin and Transcription Signal Transduction Molecular Medicine

Evolutionary Biology

Evolution of mating systems Evolutionary Ecology of Cooperation Population genetics and genomics Behavioural Ecology Sex-ratio and life history evolution

Cell and reproductive biology, andrology, endocrinology

Hormonal regulation of the male reproductive system (animal models) The role of steroid hormone receptors Cell-cell junctions in the testis Gap junctional communication in the testis

Biophysics, Physical chemistry

Single molecule fluorescence spectroscopy and microscopy, DNA nanotechnology and bionanotechnology, structural biology

Virology, Molecular biology, Cell biology, Biochemistry

Infection and Replication of Retroviruses

Food hygiene

Microbial food spoilage and hygiene, microbial interactions, (meta)genomics and (meta)transcriptomics of food spoilage communities, lactic acid bacteria and enterobacteria

Specialisation in forensic anthropology, the legal determination of identity, human anatomy and research into child sexual exploitation

Research is in novel biometrics, forensic anthropology, identity and human anatomy

Development of neuronal diversity

Immunology, Parasitology, Genetics, Molecular and Cellular Biology

malaria, mosquito, Anopheles gambiae, host-pathogen interactions, insect immunity, genetics, bioinformatics

Biophysical Chemistry & Nanobiotechnology

single molecule fluorescence spectroscopy single molecule force spectroscopy protein dynamics enzyme kinetics enzyme optimization & biocatalysis biohybrid chemistry

telomeres, telomerase, DNA repair epigenetics, stem cells, induced pluripotent stem (iPS) cells nuclear reprogramming cancer ageing, longevity, health span

Molecular microbiology, bacterial genetics, biochemistry

Evolution of bacterial pathogens Horizontal gene transfer Environmental reservoirs of facultative pathogens

Medical protein chemistry, Immunology

Immunology, the complement system, infections, cancer, autoimmune diseases, protein chemistry

Microbiology, biogeochemistry

Geomicrobiology Methane biogeochemistry Ecology of chemosynthetic habitats Microbial biodiversity Microbial processes of early diagenesis in deep-sea sediments Effects of pressure and temperature on microbial processes Pelago-benthic coupling in Polar Seas General Microbial Ecology Microbial symbiosis Deep-sea ecology Marine carbon cycle

Genetics, microbiology, molecular phytopathology

Protein transport systems, bacterial pathogens, Type-III effector proteins, signal transduction, sRNAs in Xanthomonas

Biochemistry, Biophysics

Membrane protein folding and assembly Membrane lipids Membrane protein function and regulation Protein Dynamics Synthetic Biology

Membranes and Transport

Organelle biogenesis and membane traffic; membrane proteins; protein targeting; Endoplasmic Reticulum

Wheat genetics; senescence and nutrient remobilisation; cereal grain nutritional value; genomics

Wheat grain nutritional value; genomics

Physiology of adipose tissue and obesity

Insulin resistance Inflammation Progenitor cells Angiogenesis

Regenerative Medicine, Tissue Engineering

Cardiovascular regeneration, cardiac tissue, heart valves, vessels

Developmental Neurobiology

Neuroscience Development Differentiation and Death

Embryology, developmental biology

Signal-directed cell migration Myogenesis Gene regulation Transcription factors

Biology, molecular biology, bacterial genetics

Small regulatory RNAs in gram-positive bacteria Transcription regulators in bacteria

DNA Repair, Replication, Recombination, cell cycle, DNA topology, chromatin structure

Chromatin, DNA replication, chromosome structure, DNA repair

Immunology, Parasitology

murine models of nematode infections: immune response and immune modulation

Molecular Cell Biology, Biochemistry

Cell Signaling, Ubiquitin-Proteasome System, Autophagy

Mycobacteria, macrophages, phagosome, neurons, GPCR, potassium channels, cellular signalling

Mycobacterium tuberculosis and Mycobacterium ulcerans, the molecular and cellular signalling pathways targeted by the major mycobacterial virulence factors, namely the ESX1 secretion system and the polyketide mycolactone

Trained as an experimental physicist, Lene Oddershede works at the crossroad between physics, medicine and biology. She is an expert on optical manipulation, biophysics, interaction between light and nanoparticles, and on biophysics of cells, with a special interest in stem cells.

Biophysics, nano-bio-photonics, medical physics, stem cells, nanoparticles, nanotechnology, physics, optics

Experimental Sciences; Aquatic Ecology; Water; Climate change; Limnology, Conservation and Restoration of aquatic ecosystems

Evaluation of anthropogenic impacts (e.g. climate change, eutrophication, salinization, habitat destruction) on the biodiversity and functioning in aquatic ecosystems. In particular, the study of organisms size structure and how it is affected by environmental changes. Other main interests include ecological assessment, management, conservation and restoration of aquatic ecosystems and zooplankton ecology.

Immunology

Immune regulation mucosal immunity autoimmunity alveolar epithelium host-pathogen interaction infection and autoimmunity regulatory T cells immune modulation in the context of infections

Plant biochemistry, photosynthesis

Proteins in the thylakoid membrane: structure, interaction, regulation, pigments Diatoms, cyanobacteria, spermatophytes

Ecology, biogeochemistry, plant ecology, biodiversity, greenhouse gas exchange between the biosphere and the atmosphere, ecophysiology, stable isotopes

Ecology, plant and ecosystem ecophysiology Biogeochemistry Trace gas fluxes Stable isotope ecology Functional biodiversity

Microbiology, Infection biology, Cell biology, Genomics

Infectious Diseases, Evolution of bacterial pathogens, Horizontal gene transfer, Host-pathogen interactions

Agricultural Sciences, Soil Sciences

Viticulture, Organic agriculture, Soil food webs, Biological Control, Nematology

Neuro-endocrine-immunology, Experimental rheumatology

Role of neuronal-like mechanisms used by non-neuronal cells to modulate inflammation Dopaminergic pathways in rheumatic diseases

Immunology

Immunoregulation, autoimmune disease, tumor immunity

1. Science:Neuroscience, in particular systems neuroscience, computational neuroscience, neurotechnology, science and research management2. Career paths and decisions, career counseling, workshops and lectures3. Funding for research & development in academia & industry, grant counseling

Computational neuroscience Motor control Brain-machine interfaces Neurotechnology Novel therapies

Verhaltensforschung, olfaktorische Kommunikation

Neurobiology, development of the nervous system, formation of neuronal connectivity

Characterization of gene pathways controlling early steps of the formation of the nervous system Characterization of developmental programs reactivated during tumorigenesis

genetics, molecular biology

infectious diseases, malaria, vector control, mosquito reproductive biology

NeurologyNeuroscienceTranslational Medicine

The main goal of my research is to unravel pathophysiological mechanisms and therapeutic targets for basal ganglia disorders and other related brain diseases. To pursue this goal, my research group utilise several methodologies (physiology, biochemistry, histopathology, molecular biology, brain imaging, and behavioural neuroscience). We apply these methodologies to animal models of disease that we continuously develop and optimize. We pay great attention to verify the relevance of our experimental findings to the human diseases by using different types of biomarkers. I am particularly recognised for my work in the area of Parkinson’s disease (PD) and L-DOPA-induced dyskinesia (LID), for which we have developed experimental models and key pathophysiological notions that are widely accepted today. On a more general level, I am intrigued by the brain’s capacity for plasticity and repair and interested in harnessing and boosting it for therapeutic purposes. To achieve this goal, I would like to develop innovative treatments combining pharmacological and rehabilitative principles.

molecular and cell biology

mitochondria, cellular protein homeostasis

Cancer epidemiology and genetic epidemiology

Non-genetic and genetic determinants of cancer risk and prognosis, with a focus on breast cancer and colorectal cancer Prediction of risk and prognosis Non-genetic and genetic determinants of radiatherapy toxicity, with a focus on breast cancer

Evolutionary Biology, Behavioural Ecology, Ecological Genomics

Local adaptation at small spatial scales Adaptive and non-adaptive responses to climate change Evolutionary importance of extreme climatic events Adaptation to urban habitats Sexual selection and evolution of sexual ornaments Natural selection and microevolution in natural populations Spatio-temporal fluctuations in natural selection Evolutionary ecology of bird personality Evolutionary constraints and multivariate quantitative genetics Evolution of senescence

Molecular Medicine

RNA editing / ADARs / transcriptome / cancer

Restoration of bodies of water, phytoplankton ecology, particularly that of potentially toxic cyanobacteria

Factors influencing the occurrence of varieties of phytoplankton, particularly the cyanobacteria

Cell biology, Stem cell Biology, Developmental biology of mammals

Embryonic stem cells differentiation, myogenenesis, cell cycle regulation, regenerative medicine

Molecular Biology, Molecular Genetics, Biochemistry

DNA damage response Ubiquitination Chromatin - Epigenetics Hematopoietic stem cells Cancer Stem Cells

Proteins and Biochemistry, Structural Biology and Biophysics

Protein folding, misfolding and assembly

Cell and developmental biology

Epithelial homeostasis, Tissue regeneration, Signaling, Chromatin, Adhesion, Cytoskeleton

Peptide chemistry, protein chemistry, biochemistry, molecular biology, expanded genetic code

My group investigates topologies of protein-protein interactions in the live cell by combining chemical tools and modern molecular biology techniques. We use the expanded genetic code technology to incorporate crosslinking amino acids into proteins at specific sites, and we map systematically interactions surfaces to discover regions of proximity of associated partners. We are currently focused on unveiling the binding mode of natural peptide hormones to class B GPCRs and investigating the topology of interactions involved in GPCR-associated protein complexes.

Nutrition

nutrition, food, lifecycle, ageing, obesity, pregnancy

Genetics, cellular biology, developmental biology

Control of apoptosis during development Mechanisms of apoptosis Regulation and function of mitochondrial dynamics

Cognitive Neuroscience, Psychopharmacology, Experimental Psychology, Computational Psychiatry

Chemical neuromodulation of human cognition. Cognitive control, motivation, reinforcement learning, decision making, curiosity

Signal Transduction

Signal Transduction, Membranes and Transport, Proteins and Biochemistry

Evolutionary Biology

Molecular ecology Population genetics Freshwater biology

Platelet biology

Providing mechanistic insight into the process of thrombus formation Characterising the vascular-directed effects of platelet-thrombi Effectively curtailing platelet activities in order to find new reference points for antithrombotic medication

cell biology

somatic cell reprogramming, tissue regeneration, stem cell biology, cell fusion, Wnt signaling

Gene expression/RNA processing/translation/mRNA/drug discovery/cancer biology/stem cell biology/immunity

Investigating mRNA cap function in mammals

Biochemistry, Biophysics, Plant Sciences, Photobiology

Photosynthesis in plants and algae Light-harvesting and photoprotection Acclimation mechanisms

Sustainability Science with a focus on human-Environment interactions

Trade in natural (marine) resources and its effects on local development and livelihoods Finance and Environment interactions Natural resource governance Science policy interactions

Immunology

Development, Immunology, Differentiation and Death

Plant Physiology; Biochemistry of plants; Molecular biology of plants; Plant stress metabolism; Eco-toxicology

Metal stress Oxidative stress Food safety and quality

Gene delivery technologies and retinal gene therapy

Gene delivery (Adeno-associated virus, nanoparticles) Gene therapy Optogenetics Retinal degeneration

Metabolic physiology, nutrition science

The structure and function of nutrient transport proteins, regulation of metabolism by nutrients at the level of the transcriptome, proteome and metabolome, nutrigenomics, nutrient-drug interactions.

RNA

Proteins and Biochemistry, RNA, Chromatin and Transcription, Membranes and Transport

Genetics, Molecular Medicine

Molecular Medicine, Neuroscience, Genomic and Computational Biology

Biology and Biomedicine

Neuroscience